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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0010399 through 18771 annotations produced 1 hits

NMDA receptor (Nmdar1):

Annotation Number : CG2902
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010399
Gbrowse : chr3R:1334543-1349046 (-) // 100.0 //
Probeset : 1641697_at
Accessions : protein= NP_730940;, nucleotide= NM_169059;
Pathway : 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from e
Interpro : 0004872 // receptor activity // inferred from electronic annotation /// 0004970 // ionotropic glutamate receptor activit
FlyMine data for FBgn0010399.
BDGP gene expression has embryonic in situ data for Nmdar1: 15 pix of staining in 4 body parts.
Homophila reports that CG2902 is a close match (3e-51) to human gene GLUR3;GRIA3;MRX94 (NP_015564), a gene associated with Mental retardation, X-linked 94, 300699 (3).
TRiP has 3 RNAi stocks for FBgn0010399 available for purchase.
VDRC has 3 RNAi stocks for FBgn0010399 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain330 234 of 442.50Up
Head67 84 of 4 8.70Up
Eye12 24 of 4 1.57None
Thoracicoabdominal ganglion319 44 of 441.00Up
Salivary gland3 10 of 4 0.45None
Crop4 11 of 4 0.50None
Midgut0 00 of 4 0.10Down
Tubule4 01 of 4 0.60Down
Hindgut3 10 of 4 0.50Down
Heart0 00 of 4 0.07Down
Fat body7 23 of 4 0.95None
Ovary0 00 of 4 0.10Down
Testis2 00 of 4 0.30Down
Male accessory glands6 11 of 4 0.80None
Virgin spermatheca8 12 of 4 1.11None
Mated spermatheca5 21 of 4 0.73None
Adult carcass4 10 of 4 0.60None
Larval CNS192 154 of 424.75Up
Larval Salivary gland4 00 of 4 0.61None
Larval midgut2 10 of 4 0.28Down
Larval tubule4 11 of 4 0.60None
Larval hindgut2 00 of 4 0.26Down
Larval fat body5 10 of 4 0.70None
Larval trachea0 00 of 4 0.10Down
Larval carcass3 01 of 4 0.45Down
S2 cells (growing)0 00 of 4 0.12Down
Whole fly7 04 of 4

Looking for FBgn0010399. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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