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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0010548 through 18771 annotations produced 1 hits



Fatty aldehyde dehydrogenase (Aldh-III):

Annotation Number : CG11140
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010548
Gbrowse : chr2R:3354378-3364667 (-) // 100.0 //
Probeset : 1627861_s_at
Accessions : protein= NP_610285; /// NP_724560; /// NP_724561; /// NP_724563; /// NP_724564; /// NP_724565; /// NP_724566; /// NP_995772;, nucleotide= NM_136441; /// NM_165526; /// NM_165527; /// NM_165529; /// NM_165530; /// NM_165531; /// NM_165532; /// NM_206050;
Pathway : 0005811 // lipid particle // inferred from direct assay
Interpro : "0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreducta
FlyMine data for FBgn0010548.
BDGP gene expression has embryonic in situ data for Aldh-III: 18 pix of staining in 8 body parts.
Homophila reports that CG11140 is a close match (4e-12) to human gene ALDH6A1;MMSDH (NP_005580), a gene associated with Methylmalonate semialdehyde dehydrogenase deficiency (3).
BioGrid reports that CG11140 interacts with CG11699 CG12399 CG2720 CG7070 CG9392 Dmel CR32477 .
VDRC has 2 RNAi stocks for FBgn0010548 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain205 ± 54 of 4 0.70Down
Head574 ± 104 of 4 2.10Up
Eye304 ± 144 of 4 1.09None
Thoracicoabdominal ganglion202 ± 64 of 4 0.70Down
Salivary gland296 ± 64 of 4 1.06None
Crop687 ± 164 of 4 2.50Up
Midgut274 ± 154 of 4 1.00None
Tubule303 ± 284 of 4 1.10None
Hindgut457 ± 144 of 4 1.60Up
Heart900 ± 554 of 4 3.24Up
Fat body1140 ± 554 of 4 4.10Up
Ovary100 ± 44 of 4 0.40Down
Testis218 ± 54 of 4 0.80Down
Male accessory glands97 ± 54 of 4 0.30Down
Virgin spermatheca696 ± 104 of 4 2.50Up
Mated spermatheca624 ± 574 of 4 2.24Up
Adult carcass864 ± 374 of 4 3.10Up
Larval CNS142 ± 124 of 4 0.51Down
Larval Salivary gland581 ± 334 of 4 2.09Up
Larval midgut642 ± 434 of 4 2.31Up
Larval tubule385 ± 204 of 4 1.40Up
Larval hindgut189 ± 74 of 4 0.68Down
Larval fat body489 ± 404 of 4 1.80Up
Larval trachea213 ± 174 of 4 0.77Down
Larval carcass552 ± 394 of 4 1.99Up
S2 cells (growing)330 ± 84 of 4 1.19Up
Whole fly278 ± 44 of 4

Looking for FBgn0010548. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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