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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0010611 through 18771 annotations produced 1 hits



HMG-CoA synthase (Hmgs):

Annotation Number : CG4311
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010611
Gbrowse : chr2R:12223594-12228760 (+) // 100.0 //
Probeset : 1634072_s_at
Accessions : protein= NP_524711; /// NP_725567; /// NP_725568; /// NP_725569; /// NP_725570;, nucleotide= NM_079972; /// NM_166166; /// NM_166167; /// NM_166168; /// NM_166169;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004421 // hydroxymethylglutaryl-CoA synthase a
FlyMine data for FBgn0010611.
BDGP gene expression has embryonic in situ data for Hmgs: 17 pix of staining in 12 body parts.
Homophila reports that CG4311 is a close match (1e-161) to human gene HMGCS2 (NP_005509), a gene associated with HMG-CoA synthase-2 deficiency, 605911 (3).
VDRC has 3 RNAi stocks for FBgn0010611 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain298 ± 54 of 4 0.70Down
Head368 ± 94 of 4 0.80Down
Eye198 ± 134 of 4 0.45Down
Thoracicoabdominal ganglion257 ± 84 of 4 0.60Down
Salivary gland254 ± 194 of 4 0.58Down
Crop668 ± 214 of 4 1.50Up
Midgut375 ± 164 of 4 0.90Down
Tubule127 ± 104 of 4 0.30Down
Hindgut570 ± 294 of 4 1.30Up
Heart843 ± 264 of 4 1.92Up
Fat body1328 ± 714 of 4 3.02Up
Ovary512 ± 134 of 4 1.20Up
Testis142 ± 74 of 4 0.30Down
Male accessory glands512 ± 464 of 4 1.20None
Virgin spermatheca1074 ± 1054 of 4 2.44Up
Mated spermatheca941 ± 974 of 4 2.14Up
Adult carcass704 ± 424 of 4 1.60Up
Larval CNS293 ± 184 of 4 0.67Down
Larval Salivary gland246 ± 104 of 4 0.56Down
Larval midgut878 ± 464 of 4 1.99Up
Larval tubule106 ± 24 of 4 0.20Down
Larval hindgut525 ± 494 of 4 1.19None
Larval fat body108 ± 74 of 4 0.20Down
Larval trachea295 ± 184 of 4 0.67Down
Larval carcass577 ± 234 of 4 1.31Up
S2 cells (growing)1221 ± 294 of 4 2.77Up
Whole fly440 ± 134 of 4

Looking for FBgn0010611. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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