FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0011211 through 18771 annotations produced 2 hits

aquaporin /// mitochondrial ATP synthase alpha subunit (AQP /// blw):

Annotation Number : CG12251
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033807
Gbrowse : chr2R:9099841-9101433 (-) // 99.59 //
Probeset : 1626560_at
Accessions : protein= NP_001163140; /// NP_523728; /// NP_726243;, nucleotide= NM_001169669; /// NM_079004; /// NM_166554;
Pathway : engulfment // inferred from mutant phenotype /// 0007286 // spermatid development // inferred from mutant phenotype ///
Interpro : catalytic core F(1) // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from el
FlyMine data for FBgn0033807.
BDGP gene expression has embryonic in situ data for blw: 10 pix of staining in 12 body parts.
VDRC has 1 RNAi stocks for FBgn0033807 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	6 ± 1	1 of 4	0.00	Down
Head	206 ± 4	4 of 4	0.70	None
Eye	29 ± 3	4 of 4	0.11	Down
Thoracicoabdominal ganglion	41 ± 6	4 of 4	0.10	Down
Salivary gland	18 ± 4	0 of 4	0.07	Down
Crop	632 ± 16	4 of 4	2.30	Up
Midgut	44 ± 2	4 of 4	0.20	Down
Tubule	14 ± 1	1 of 4	0.10	Down
Hindgut	233 ± 6	4 of 4	0.80	None
Heart	338 ± 19	4 of 4	1.23	None
Fat body	18 ± 3	3 of 4	0.07	Down
Ovary	2 ± 0	1 of 4	0.00	Down
Testis	141 ± 7	4 of 4	0.50	Down
Male accessory glands	129 ± 12	4 of 4	0.50	Down
Virgin spermatheca	26 ± 1	4 of 4	0.10	Down
Mated spermatheca	41 ± 4	4 of 4	0.15	Down
Adult carcass	1008 ± 82	4 of 4	3.70	Up
Larval CNS	5 ± 1	0 of 4	0.02	Down
Larval Salivary gland	3 ± 0	0 of 4	0.01	Down
Larval midgut	9 ± 1	1 of 4	0.03	Down
Larval tubule	4 ± 1	0 of 4	0.00	Down
Larval hindgut	73 ± 5	4 of 4	0.27	Down
Larval fat body	34 ± 14	4 of 4	0.10	Down
Larval trachea	16 ± 10	3 of 4	0.06	Down
Larval carcass	338 ± 20	4 of 4	1.23	None
S2 cells (growing)	6 ± 0	1 of 4	0.02	Down
Whole fly	276 ± 36	4 of 4

chr2R:18686558-18689691 (+) // 100.0 // (mitochondrial ATP synthase alpha subunit):

Annotation Number : CG3612
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1636548_at
Accessions : protein= , nucleotide= NP_726243;
Pathway : "0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from el
Interpro : engulfment // inferred from mutant phenotype /// 0007286 // spermatid development // inferred from mutant phenotype ///
FlyMine data for full length.
Homophila reports that CG3612 is a close match (1e-22) to human gene ATP6B1;VPP3 (NP_001683), a gene associated with Renal tubular acidosis with deafness, 267300 (3).
BioGrid reports that CG3612 interacts with CG6569 CG4654 CG6376 .

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	2769 ± 61	4 of 4	0.90	None
Head	3463 ± 63	4 of 4	1.10	Up
Eye	3443 ± 42	4 of 4	1.11	None
Thoracicoabdominal ganglion	3719 ± 72	4 of 4	1.20	Up
Salivary gland	9013 ± 233	4 of 4	2.90	Up
Crop	4047 ± 185	4 of 4	1.30	Up
Midgut	3516 ± 60	4 of 4	1.10	Up
Tubule	5474 ± 86	4 of 4	1.80	Up
Hindgut	4630 ± 122	4 of 4	1.50	Up
Heart	4228 ± 196	4 of 4	1.36	Up
Fat body	5347 ± 626	4 of 4	1.72	Up
Ovary	2346 ± 42	4 of 4	0.80	Down
Testis	811 ± 23	4 of 4	0.30	Down
Male accessory glands	3364 ± 31	4 of 4	1.10	None
Virgin spermatheca	6418 ± 138	4 of 4	2.07	Up
Mated spermatheca	6445 ± 197	4 of 4	2.08	Up
Adult carcass	6129 ± 355	4 of 4	2.00	Up
Larval CNS	2259 ± 100	4 of 4	0.73	Down
Larval Salivary gland	3974 ± 76	4 of 4	1.28	Up
Larval midgut	4692 ± 123	4 of 4	1.51	Up
Larval tubule	2775 ± 263	4 of 4	0.90	None
Larval hindgut	4737 ± 49	4 of 4	1.53	Up
Larval fat body	2042 ± 169	4 of 4	0.70	Down
Larval trachea	2527 ± 123	4 of 4	0.81	Down
Larval carcass	4540 ± 412	4 of 4	1.46	Up
S2 cells (growing)	2259 ± 47	4 of 4	0.73	Down
Whole fly	3102 ± 117	4 of 4

Looking for FBgn0011211. 2 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720