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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0011296 through 18771 annotations produced 3 hits



lethal (2) essential for life (l(2)efl):

Annotation Number : CG4533
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0011296
Gbrowse : chr2R:19572320-19573044 (-) // 100.0 //
Probeset : 1626416_a_at
Accessions : protein= NP_523827; /// NP_726354;, nucleotide= NM_079103; /// NM_166620;
Interpro : 0042802 // identical protein binding // inferred from physical interaction
FlyMine data for FBgn0011296.
BDGP gene expression has embryonic in situ data for l(2)efl: 21 pix of staining in 2 body parts.
Homophila reports that CG4533 is a close match (3e-14) to human gene CMT2F;HMN2B;HSP27;HSPB1 (NP_001531), a gene associated with Charcot-Marie-Tooth disease, axonal, type 2F, 606595 (3);Neuropathy, distal hereditary motor, type IIB, 608634 (3).
BioGrid reports that CG4533 interacts with CG4533 CG5660 CG8219 .
TRiP has 1 RNAi stocks for FBgn0011296 available for purchase.
VDRC has 3 RNAi stocks for FBgn0011296 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain42 ± 34 of 4 0.10Down
Head445 ± 564 of 4 1.00None
Eye39 ± 54 of 4 0.09Down
Thoracicoabdominal ganglion34 ± 44 of 4 0.10Down
Salivary gland11 ± 30 of 4 0.03Down
Crop5056 ± 2774 of 411.70Up
Midgut824 ± 344 of 4 1.90Up
Tubule96 ± 304 of 4 0.20Down
Hindgut2861 ± 564 of 4 6.60Up
Heart1473 ± 1084 of 4 3.42Up
Fat body54 ± 104 of 4 0.13Down
Ovary26 ± 14 of 4 0.10Down
Testis117 ± 74 of 4 0.30Down
Male accessory glands588 ± 334 of 4 1.40Up
Virgin spermatheca31 ± 24 of 4 0.07Down
Mated spermatheca59 ± 134 of 4 0.14Down
Adult carcass1119 ± 1144 of 4 2.60Up
Larval CNS18 ± 14 of 4 0.04Down
Larval Salivary gland22 ± 43 of 4 0.05Down
Larval midgut1285 ± 634 of 4 2.99Up
Larval tubule97 ± 154 of 4 0.20Down
Larval hindgut3196 ± 994 of 4 7.43Up
Larval fat body14 ± 32 of 4 0.00Down
Larval trachea219 ± 1444 of 4 0.51None
Larval carcass4097 ± 2714 of 4 9.52Up
S2 cells (growing)10 ± 01 of 4 0.02Down
Whole fly430 ± 284 of 4



lethal (2) essential for life (l(2)efl):

Annotation Number : CG4533
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0011296
Gbrowse : chr2R:19572173-19573063 (-) // 100.0 //
Probeset : 1627242_at
Accessions : protein= NP_523827; /// NP_726354;, nucleotide= NM_079103; /// NM_166620;
Interpro : 0042802 // identical protein binding // inferred from physical interaction
FlyMine data for FBgn0011296.
BDGP gene expression has embryonic in situ data for l(2)efl: 21 pix of staining in 2 body parts.
Homophila reports that CG4533 is a close match (3e-14) to human gene CMT2F;HMN2B;HSP27;HSPB1 (NP_001531), a gene associated with Charcot-Marie-Tooth disease, axonal, type 2F, 606595 (3);Neuropathy, distal hereditary motor, type IIB, 608634 (3).
BioGrid reports that CG4533 interacts with CG4533 CG5660 CG8219 .
TRiP has 1 RNAi stocks for FBgn0011296 available for purchase.
VDRC has 3 RNAi stocks for FBgn0011296 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain130 ± 84 of 4 0.10Down
Head1609 ± 1924 of 4 1.10None
Eye214 ± 274 of 4 0.15Down
Thoracicoabdominal ganglion131 ± 114 of 4 0.10Down
Salivary gland80 ± 161 of 4 0.06Down
Crop6360 ± 4074 of 4 4.40Up
Midgut2510 ± 954 of 4 1.80Up
Tubule678 ± 2214 of 4 0.50Down
Hindgut4565 ± 974 of 4 3.20Up
Heart4540 ± 1964 of 4 3.18Up
Fat body319 ± 1224 of 4 0.22Down
Ovary82 ± 84 of 4 0.10Down
Testis331 ± 224 of 4 0.20Down
Male accessory glands2555 ± 864 of 4 1.80Up
Virgin spermatheca377 ± 304 of 4 0.26Down
Mated spermatheca734 ± 1854 of 4 0.51Down
Adult carcass3294 ± 3754 of 4 2.30Up
Larval CNS71 ± 104 of 4 0.05Down
Larval Salivary gland90 ± 114 of 4 0.06Down
Larval midgut3987 ± 1034 of 4 2.79Up
Larval tubule398 ± 424 of 4 0.30Down
Larval hindgut4432 ± 1124 of 4 3.10Up
Larval fat body48 ± 151 of 4 0.00Down
Larval trachea839 ± 5154 of 4 0.59None
Larval carcass4949 ± 4314 of 4 3.46Up
S2 cells (growing)14 ± 50 of 4 0.01Down
Whole fly1429 ± 614 of 4



lethal (2) essential for life (l(2)efl):

Annotation Number : CG4533
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0011296
Gbrowse : chr2R:19572320-19573044 (-) // 100.0 //
Probeset : 1635952_at
Accessions : protein= NP_523827; /// NP_726354;, nucleotide= NM_079103; /// NM_166620;
Interpro : 0042802 // identical protein binding // inferred from physical interaction
FlyMine data for FBgn0011296.
BDGP gene expression has embryonic in situ data for l(2)efl: 21 pix of staining in 2 body parts.
Homophila reports that CG4533 is a close match (3e-14) to human gene CMT2F;HMN2B;HSP27;HSPB1 (NP_001531), a gene associated with Charcot-Marie-Tooth disease, axonal, type 2F, 606595 (3);Neuropathy, distal hereditary motor, type IIB, 608634 (3).
BioGrid reports that CG4533 interacts with CG4533 CG5660 CG8219 .
TRiP has 1 RNAi stocks for FBgn0011296 available for purchase.
VDRC has 3 RNAi stocks for FBgn0011296 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain2 ± 10 of 4 0.60None
Head4 ± 00 of 4 1.60None
Eye3 ± 00 of 4 1.16None
Thoracicoabdominal ganglion2 ± 10 of 4 0.60None
Salivary gland12 ± 10 of 4 3.91Up
Crop102 ± 104 of 432.90Up
Midgut15 ± 11 of 4 4.80Up
Tubule8 ± 30 of 4 2.80None
Hindgut43 ± 44 of 414.00Up
Heart31 ± 114 of 410.05None
Fat body7 ± 31 of 4 2.27None
Ovary0 ± 00 of 4 0.10None
Testis4 ± 02 of 4 1.50None
Male accessory glands13 ± 51 of 4 4.50None
Virgin spermatheca1 ± 00 of 4 0.40None
Mated spermatheca3 ± 10 of 4 1.12None
Adult carcass20 ± 61 of 4 6.70None
Larval CNS3 ± 10 of 4 0.97None
Larval Salivary gland1 ± 10 of 4 0.60None
Larval midgut14 ± 20 of 4 4.65Up
Larval tubule2 ± 00 of 4 0.60None
Larval hindgut31 ± 34 of 410.05Up
Larval fat body6 ± 20 of 4 2.10None
Larval trachea2 ± 20 of 4 0.92None
Larval carcass102 ± 134 of 433.06Up
S2 cells (growing)0 ± 00 of 4 0.23None
Whole fly3 ± 10 of 4

Looking for FBgn0011296. 3 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

measure downtime