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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0011704 through 18771 annotations produced 1 hits

ribonucleoside-diphosphate reductase small subunit (RnrS):

Annotation Number : CG8975
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0011704
Gbrowse : chr2R:7870645-7872948 (-) // 100.0 //
Probeset : 1635409_at
Accessions : protein= NP_525111;, nucleotide= NM_080372;
Pathway : 0005737 // cytoplasm // inferred from electronic annotation /// 0005971 // ribonucleoside-diphosphate reductase complex
Interpro : 0004748 // ribonucleoside-diphosphate reductase activity // inferred from sequence or structural similarity /// 0004748
FlyMine data for FBgn0011704.
BDGP gene expression has embryonic in situ data for RnrS: 26 pix of staining in 26 body parts.
Homophila reports that CG8975 is a close match (1e-138) to human gene RRM2B;P53R2 (NP_056528), a gene associated with Mitochondrial DNA depletion syndrome, encephalomyopathic form, with renal tubulopathy, 612075 (3).
BioGrid reports that CG8975 interacts with CG9083 .
TRiP has 1 RNAi stocks for FBgn0011704 available for purchase.
VDRC has 1 RNAi stocks for FBgn0011704 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain11 14 of 4 0.00Down
Head70 74 of 4 0.10Down
Eye36 24 of 4 0.04Down
Thoracicoabdominal ganglion10 13 of 4 0.00Down
Salivary gland332 164 of 4 0.34Down
Crop62 34 of 4 0.10Down
Midgut225 74 of 4 0.20Down
Tubule498 444 of 4 0.50Down
Hindgut217 174 of 4 0.20Down
Heart71 34 of 4 0.07Down
Fat body82 414 of 4 0.08Down
Ovary1903 244 of 4 1.90Up
Testis64 34 of 4 0.10Down
Male accessory glands308 164 of 4 0.30Down
Virgin spermatheca188 24 of 4 0.19Down
Mated spermatheca167 204 of 4 0.17Down
Adult carcass85 134 of 4 0.10Down
Larval CNS631 434 of 4 0.64Down
Larval Salivary gland1474 784 of 4 1.50Up
Larval midgut228 64 of 4 0.23Down
Larval tubule357 264 of 4 0.40Down
Larval hindgut378 244 of 4 0.38Down
Larval fat body525 594 of 4 0.50Down
Larval trachea653 1154 of 4 0.67Down
Larval carcass329 114 of 4 0.34Down
S2 cells (growing)856 284 of 4 0.87None
Whole fly982 624 of 4

Looking for FBgn0011704. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

measure downtime