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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0013308 through 18771 annotations produced 1 hits

Ornithine decarboxylase 2 (Odc2):

Annotation Number : CG8719
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0013308
Gbrowse : chr2R:3894768-3896569 (+) // 100.0 //
Probeset : 1631439_at
Accessions : protein= NP_477053;, nucleotide= NM_057705;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004586 // ornithine decarboxylase activity //
FlyMine data for FBgn0013308.
Homophila reports that CG8719 is a close match (8e-78) to human gene ODC1 (NP_002530), a gene associated with {Colonic adenoma recurrence, reduced risk of}, 114500 (3).
VDRC has 4 RNAi stocks for FBgn0013308 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain2 00 of 4 0.30None
Head13 14 of 4 1.80None
Eye14 14 of 4 2.03None
Thoracicoabdominal ganglion4 00 of 4 0.60None
Salivary gland5 30 of 4 0.79None
Crop1 00 of 4 0.20None
Midgut2 10 of 4 0.30None
Tubule2 10 of 4 0.40Down
Hindgut3 00 of 4 0.50None
Heart121 194 of 416.45Up
Fat body209 94 of 428.44Up
Ovary0 00 of 4 0.10None
Testis21 14 of 4 3.00Up
Male accessory glands6 10 of 4 0.90None
Virgin spermatheca217 224 of 429.55Up
Mated spermatheca161 204 of 421.95Up
Adult carcass45 64 of 4 6.10Up
Larval CNS1 10 of 4 0.16None
Larval Salivary gland3 10 of 4 0.42None
Larval midgut2 10 of 4 0.38None
Larval tubule5 00 of 4 0.70None
Larval hindgut4 11 of 4 0.63None
Larval fat body178 94 of 424.20Up
Larval trachea2 10 of 4 0.29None
Larval carcass2 10 of 4 0.32None
S2 cells (growing)2 00 of 4 0.27None
Whole fly7 21 of 4

Looking for FBgn0013308. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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