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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0013770 through 18771 annotations produced 1 hits



Cathepsin L (Cp1):

Annotation Number : CG6692
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0013770
Gbrowse : chr2R:9848163-9855496 (+) // 100.0 //
Probeset : 1625264_s_at
Accessions : protein= NP_523735; /// NP_725347; /// NP_725348;, nucleotide= NM_079011; /// NM_166026; /// NM_166027;
Pathway : 0005764 // lysosome // non-traceable author statement /// 0005764 // lysosome // inferred from electronic annotation ///
Interpro : 0004197 // cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0004197 // cystei
FlyMine data for FBgn0013770.
Homophila reports that CG6692 is a close match (1e-23) to human gene CPPI;CTSC;HMS;JPD;PALS;PLS (NP_001805), a gene associated with Haim-Munk syndrome, 245010 (3);Papillon-Lefevre syndrome, 245000 (3);Periodontitis, juvenile, 170650 (3).
BioGrid reports that CG6692 interacts with CG9163 CG9520 .
TRiP has 2 RNAi stocks for FBgn0013770 available for purchase.
VDRC has 2 RNAi stocks for FBgn0013770 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1105 ± 104 of 4 0.60Down
Head2500 ± 794 of 4 1.30Up
Eye2495 ± 2924 of 4 1.26None
Thoracicoabdominal ganglion1164 ± 44 of 4 0.60Down
Salivary gland1580 ± 844 of 4 0.80Down
Crop1782 ± 324 of 4 0.90Down
Midgut2288 ± 584 of 4 1.20Up
Tubule1919 ± 404 of 4 1.00None
Hindgut1986 ± 234 of 4 1.00None
Heart7471 ± 6034 of 4 3.77Up
Fat body4448 ± 4834 of 4 2.25Up
Ovary1871 ± 334 of 4 0.90None
Testis1068 ± 424 of 4 0.50Down
Male accessory glands3043 ± 1754 of 4 1.50Up
Virgin spermatheca5025 ± 1644 of 4 2.54Up
Mated spermatheca4235 ± 1694 of 4 2.14Up
Adult carcass4350 ± 1024 of 4 2.20Up
Larval CNS839 ± 424 of 4 0.42Down
Larval Salivary gland1022 ± 474 of 4 0.52Down
Larval midgut2865 ± 3204 of 4 1.45None
Larval tubule4350 ± 824 of 4 2.20Up
Larval hindgut2548 ± 1794 of 4 1.29Up
Larval fat body2236 ± 4334 of 4 1.10None
Larval trachea3603 ± 5964 of 4 1.82Up
Larval carcass2275 ± 2344 of 4 1.15None
S2 cells (growing)3163 ± 694 of 4 1.60Up
Whole fly1980 ± 584 of 4

Looking for FBgn0013770. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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