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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0014032 through 18771 annotations produced 1 hits

sepiapterin reductase (Sptr):

Annotation Number : CG12117
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0014032
Gbrowse : chrX:8357337-8359030 (-) // 100.0 //
Probeset : 1632179_at
Accessions : protein= NP_727265;, nucleotide= NM_167157;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004757 // sepiapterin reductase activity // in
FlyMine data for FBgn0014032.
BDGP gene expression has embryonic in situ data for Sptr: 4 pix of staining in 1 body parts.
Homophila reports that CG12117 is a close match (1e-26) to human gene SPR (NP_003115), a gene associated with Sepiapterin reductase deficiency (3).
TRiP has 1 RNAi stocks for FBgn0014032 available for purchase.
VDRC has 3 RNAi stocks for FBgn0014032 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain118 44 of 4 0.80Down
Head196 64 of 4 1.30Up
Eye212 124 of 4 1.41Up
Thoracicoabdominal ganglion102 34 of 4 0.70Down
Salivary gland503 104 of 4 3.35Up
Crop539 214 of 4 3.60Up
Midgut127 44 of 4 0.90Down
Tubule110 284 of 4 0.70None
Hindgut422 144 of 4 2.80Up
Heart78 24 of 4 0.52Down
Fat body95 304 of 4 0.63Down
Ovary215 64 of 4 1.40Up
Testis31 04 of 4 0.20Down
Male accessory glands118 74 of 4 0.80Down
Virgin spermatheca203 174 of 4 1.35Up
Mated spermatheca178 114 of 4 1.19None
Adult carcass166 84 of 4 1.10None
Larval CNS120 104 of 4 0.80Down
Larval Salivary gland174 134 of 4 1.16None
Larval midgut42 24 of 4 0.28Down
Larval tubule40 24 of 4 0.30Down
Larval hindgut175 54 of 4 1.16Up
Larval fat body34 24 of 4 0.20Down
Larval trachea259 134 of 4 1.72Up
Larval carcass250 34 of 4 1.66Up
S2 cells (growing)54 34 of 4 0.36Down
Whole fly150 64 of 4

Looking for FBgn0014032. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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