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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0015011 through 18771 annotations produced 1 hits

AdoHcyase-like (Ahcy89E):

Annotation Number : CG8956
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015011
Gbrowse : chr3R:12804150-12807754 (-) // 100.0 //
Probeset : 1624017_at
Accessions : protein= NP_996221; /// NP_996222;, nucleotide= NM_206499; /// NM_206500;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004013 // adenosylhomocysteinase activity // i
FlyMine data for FBgn0015011.
BDGP gene expression has embryonic in situ data for Ahcy89E: 18 pix of staining in 6 body parts.
Homophila reports that CG8956 is a close match (8e-124) to human gene AHCY;SAHH (NP_000678), a gene associated with Hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase (3).
VDRC has 2 RNAi stocks for FBgn0015011 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain25 24 of 4 0.50None
Head100 114 of 4 1.90Up
Eye188 144 of 4 3.66Up
Thoracicoabdominal ganglion54 34 of 4 1.10None
Salivary gland103 74 of 4 2.00Up
Crop22 34 of 4 0.40None
Midgut199 74 of 4 3.90Up
Tubule664 664 of 412.90Up
Hindgut2204 424 of 442.80Up
Heart24 24 of 4 0.47None
Fat body40 123 of 4 0.78None
Ovary3 00 of 4 0.10Down
Testis5 00 of 4 0.10Down
Male accessory glands177 144 of 4 3.50Up
Virgin spermatheca26 24 of 4 0.52None
Mated spermatheca27 23 of 4 0.53None
Adult carcass66 34 of 4 1.30None
Larval CNS3 10 of 4 0.07Down
Larval Salivary gland12 50 of 4 0.23Down
Larval midgut255 194 of 4 4.97Up
Larval tubule679 204 of 413.20Up
Larval hindgut3302 814 of 464.19Up
Larval fat body507 514 of 4 9.90Up
Larval trachea79 124 of 4 1.55None
Larval carcass275 744 of 4 5.35None
S2 cells (growing)8 11 of 4 0.16Down
Whole fly51 94 of 4

Looking for FBgn0015011. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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