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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0015033 through 18771 annotations produced 1 hits



Cytochrome P450-4d8 (Cyp4d8):

Annotation Number : CG4321
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015033
Gbrowse : chr3L:7486648-7489279 (-) // 100.0 //
Probeset : 1626198_at
Accessions : protein= NP_523961;, nucleotide= NM_079237;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0015033.
Homophila reports that CG4321 is a close match (2e-11) to human gene CPD6;CYP2D6;P450DB1 (NP_001020332), a gene associated with Codeine sensitivity (3);Debrisoquine sensitivity (3);{?Parkinsonism, susceptibility to} (1).
VDRC has 3 RNAi stocks for FBgn0015033 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain4 ± 10 of 4 0.10Down
Head119 ± 134 of 4 2.80Up
Eye59 ± 14 of 4 1.41Up
Thoracicoabdominal ganglion4 ± 10 of 4 0.10Down
Salivary gland13 ± 30 of 4 0.31Down
Crop10 ± 30 of 4 0.20Down
Midgut247 ± 124 of 4 5.80Up
Tubule168 ± 224 of 4 4.00Up
Hindgut14 ± 21 of 4 0.30Down
Heart98 ± 44 of 4 2.33Up
Fat body29 ± 44 of 4 0.69Down
Ovary6 ± 11 of 4 0.20Down
Testis39 ± 24 of 4 0.90None
Male accessory glands155 ± 114 of 4 3.70Up
Virgin spermatheca37 ± 34 of 4 0.89None
Mated spermatheca26 ± 43 of 4 0.62Down
Adult carcass89 ± 44 of 4 2.10Up
Larval CNS4 ± 10 of 4 0.10Down
Larval Salivary gland9 ± 21 of 4 0.23Down
Larval midgut656 ± 604 of 415.47Up
Larval tubule34 ± 14 of 4 0.80None
Larval hindgut13 ± 12 of 4 0.32Down
Larval fat body48 ± 84 of 4 1.10None
Larval trachea6 ± 41 of 4 0.16Down
Larval carcass10 ± 31 of 4 0.25Down
S2 cells (growing)3 ± 00 of 4 0.07Down
Whole fly42 ± 34 of 4

Looking for FBgn0015033. 1 entries matched from 18771, in 0 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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