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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0015277 through 18771 annotations produced 1 hits



dPI 3-kinase (Pi3K59F):

Annotation Number : CG5373
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015277
Gbrowse : chr2R:19448016-19451570 (+) // 100.0 //
Probeset : 1625678_at
Accessions : protein= NP_477133;, nucleotide= NM_057785;
Pathway : "0005942 // phosphoinositide 3-kinase complex // inferred from electronic annotation /// 0035032 // phosphoinositide 3-k
Interpro : class III // non-traceable author statement 0004428 // inositol or phosphatidylinositol kinase activity // inferred fro
FlyMine data for FBgn0015277.
BDGP gene expression has embryonic in situ data for Pi3K59F: 4 pix of staining in 1 body parts.
Homophila reports that CG5373 is a close match (2e-40) to human gene PIK3CA (NP_006209), a gene associated with Breast cancer, somatic, 114480 (3);Colorectal cancer, somatic, 114500 (3);Gastric cancer, somatic, 137215 (3);Hepatocellular carcinoma, somatic, 114550 (3);Keratosis, seborrheic, somatic, 182000 (3);Nevus, epidermal, 162900 (3);Nonsmall cell lung cancer, somatic, 211980 (3);Ovarian cancer, somatic, 604370 (3).
TRiP has 2 RNAi stocks for FBgn0015277 available for purchase.
VDRC has 1 RNAi stocks for FBgn0015277 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain100 ± 34 of 4 2.00Up
Head75 ± 54 of 4 1.50Up
Eye78 ± 34 of 4 1.59Up
Thoracicoabdominal ganglion111 ± 34 of 4 2.20Up
Salivary gland144 ± 64 of 4 2.93Up
Crop88 ± 84 of 4 1.80Up
Midgut76 ± 23 of 4 1.50Up
Tubule107 ± 34 of 4 2.20Up
Hindgut107 ± 64 of 4 2.20Up
Heart55 ± 14 of 4 1.12None
Fat body66 ± 24 of 4 1.34Up
Ovary50 ± 24 of 4 1.00None
Testis8 ± 10 of 4 0.20Down
Male accessory glands103 ± 44 of 4 2.10Up
Virgin spermatheca91 ± 34 of 4 1.86Up
Mated spermatheca81 ± 74 of 4 1.66Up
Adult carcass82 ± 74 of 4 1.70Up
Larval CNS54 ± 44 of 4 1.10None
Larval Salivary gland47 ± 34 of 4 0.96None
Larval midgut50 ± 40 of 4 1.03None
Larval tubule105 ± 24 of 4 2.10Up
Larval hindgut59 ± 44 of 4 1.21None
Larval fat body56 ± 54 of 4 1.10None
Larval trachea48 ± 94 of 4 0.99None
Larval carcass35 ± 51 of 4 0.71None
S2 cells (growing)90 ± 24 of 4 1.83Up
Whole fly49 ± 24 of 4

Looking for FBgn0015277. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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