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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0015320 through 18771 annotations produced 1 hits

Ubiquitin conjugating enzyme 2 (UbcD2):

Annotation Number : CG6720
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015320
Gbrowse : chr2L:10765561-10768005 (-) // 100.0 //
Probeset : 1637679_s_at
Accessions : protein= NP_477137; /// NP_723616;, nucleotide= NM_057789; /// NM_164943;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein ligase activity //
FlyMine data for FBgn0015320.
BDGP gene expression has embryonic in situ data for UbcD2: 12 pix of staining in 16 body parts.
Homophila reports that CG6720 is a close match (1e-11) to human gene RAD6A;UBE2A (NP_861427), a gene associated with Mental retardation, X-linked syndromic (3).
BioGrid reports that CG6720 interacts with CG8264 CG9083 CG9415 .
VDRC has 1 RNAi stocks for FBgn0015320 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain333 174 of 4 0.60Down
Head316 254 of 4 0.60Down
Eye273 34 of 4 0.52Down
Thoracicoabdominal ganglion423 204 of 4 0.80Down
Salivary gland260 54 of 4 0.50Down
Crop336 204 of 4 0.60Down
Midgut280 54 of 4 0.50Down
Tubule236 164 of 4 0.50Down
Hindgut225 94 of 4 0.40Down
Heart306 284 of 4 0.58Down
Fat body600 564 of 4 1.15None
Ovary837 114 of 4 1.60Up
Testis645 344 of 4 1.20Up
Male accessory glands382 104 of 4 0.70Down
Virgin spermatheca400 334 of 4 0.77Down
Mated spermatheca468 354 of 4 0.89None
Adult carcass252 94 of 4 0.50Down
Larval CNS1240 1404 of 4 2.37Up
Larval Salivary gland659 634 of 4 1.26None
Larval midgut514 74 of 4 0.98None
Larval tubule592 284 of 4 1.10None
Larval hindgut715 474 of 4 1.37Up
Larval fat body599 404 of 4 1.10None
Larval trachea554 224 of 4 1.06None
Larval carcass598 114 of 4 1.14None
S2 cells (growing)1101 424 of 4 2.10Up
Whole fly523 314 of 4

Looking for FBgn0015320. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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