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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0015380 through 18771 annotations produced 1 hits

derailed (drl):

Annotation Number : CG17348
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015380
Gbrowse : chr2L:19190345-19208615 (+) // 100.0 //
Probeset : 1624297_at
Accessions : protein= NP_477139;, nucleotide= NM_057791;
Pathway : 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0015380.
BDGP gene expression has embryonic in situ data for drl: 37 pix of staining in 29 body parts.
Homophila reports that CG17348 is a close match (1e-14) to human gene BRAF (NP_004324), a gene associated with Adenocarcinoma of lung, somatic, 211980 (3);Cardiofaciocutaneous syndrome, 115150 (3);Colorectal cancer, somatic (3);Melanoma, melignant, somatic (3);Nonsmall cell lung cancer, somatic (3).
BioGrid reports that CG17348 interacts with CG2246 CG5410 CG2102 CG17559 CG6407 .
TRiP has 2 RNAi stocks for FBgn0015380 available for purchase.
VDRC has 4 RNAi stocks for FBgn0015380 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain411 34 of 410.90Up
Head109 74 of 4 2.90Up
Eye99 24 of 4 2.65Up
Thoracicoabdominal ganglion427 174 of 411.30Up
Salivary gland37 34 of 4 0.99None
Crop117 44 of 4 3.10Up
Midgut33 14 of 4 0.90None
Tubule31 44 of 4 0.80None
Hindgut23 14 of 4 0.60Down
Heart19 14 of 4 0.51Down
Fat body12 43 of 4 0.33Down
Ovary12 04 of 4 0.30Down
Testis8 14 of 4 0.20Down
Male accessory glands37 34 of 4 1.00None
Virgin spermatheca17 04 of 4 0.47Down
Mated spermatheca19 24 of 4 0.52Down
Adult carcass23 34 of 4 0.60Down
Larval CNS726 764 of 419.22Up
Larval Salivary gland9 03 of 4 0.24Down
Larval midgut10 24 of 4 0.27Down
Larval tubule50 34 of 4 1.30None
Larval hindgut9 04 of 4 0.24Down
Larval fat body8 11 of 4 0.20Down
Larval trachea339 594 of 4 8.99Up
Larval carcass50 34 of 4 1.34None
S2 cells (growing)6 04 of 4 0.18Down
Whole fly37 44 of 4

Looking for FBgn0015380. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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