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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0015400 through 18771 annotations produced 1 hits

Kekkon-2 (kek2):

Annotation Number : CG4977
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015400
Gbrowse : chr2L:11621818-11626131 (+) // 99.88 //
Probeset : 1630617_at
Accessions : protein= NP_523551;, nucleotide= NM_078827;
Pathway : 0005886 // plasma membrane // inferred from sequence or structural similarity
Interpro : 0005515 // protein binding // inferred from electronic annotation
FlyMine data for FBgn0015400.
Homophila reports that CG4977 is a close match (8e-11) to human gene TIL4;TLR2 (NP_003255), a gene associated with {Colorectal cancer, susceptibility to}, 114500 (3);{Leprosy, susceptibility to}, 246300 (3).
BioGrid reports that CG4977 interacts with CG5271 .
TRiP has 1 RNAi stocks for FBgn0015400 available for purchase.
VDRC has 6 RNAi stocks for FBgn0015400 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain155 44 of 416.80Up
Head18 24 of 4 2.00Up
Eye20 34 of 4 2.23Up
Thoracicoabdominal ganglion109 84 of 411.80Up
Salivary gland15 60 of 4 1.64None
Crop8 10 of 4 0.90None
Midgut4 10 of 4 0.50Down
Tubule7 00 of 4 0.80Down
Hindgut5 10 of 4 0.50None
Heart6 03 of 4 0.70None
Fat body10 22 of 4 1.18None
Ovary2 00 of 4 0.30Down
Testis3 00 of 4 0.30Down
Male accessory glands5 10 of 4 0.60None
Virgin spermatheca3 10 of 4 0.38Down
Mated spermatheca6 00 of 4 0.68None
Adult carcass10 20 of 4 1.10None
Larval CNS69 44 of 4 7.48Up
Larval Salivary gland3 10 of 4 0.35Down
Larval midgut4 20 of 4 0.49None
Larval tubule2 00 of 4 0.30Down
Larval hindgut4 10 of 4 0.46Down
Larval fat body5 20 of 4 0.60None
Larval trachea1 10 of 4 0.20Down
Larval carcass2 10 of 4 0.31Down
S2 cells (growing)4 00 of 4 0.46Down
Whole fly9 12 of 4

Looking for FBgn0015400. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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