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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0015570 through 18771 annotations produced 1 hits



fragment B (alpha-Est2):

Annotation Number : CG2505
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015570
Gbrowse : chr3R:3368465-3370956 (+) // 100.0 //
Probeset : 1633196_at
Accessions : protein= NP_524268;, nucleotide= NM_079544;
Pathway : 0005811 // lipid particle // inferred from direct assay
Interpro : 0004091 // carboxylesterase activity // inferred from sequence or structural similarity /// 0004091 // carboxylesterase
FlyMine data for FBgn0015570.
BDGP gene expression has embryonic in situ data for alpha-Est2: 12 pix of staining in 2 body parts.
Homophila reports that CG2505 is a close match (3e-15) to human gene AITD3;TG (NP_003226), a gene associated with Goiter, adolescent multinodular (1);Goiter, nonendemic, simple (3);Hypothyroidism, hereditary congenital (3);{Autoimmune thyroid disease, susceptibility to 3}, 608175 (3).
VDRC has 2 RNAi stocks for FBgn0015570 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain6 ± 20 of 4 0.10Down
Head304 ± 324 of 4 3.60Up
Eye99 ± 124 of 4 1.18None
Thoracicoabdominal ganglion9 ± 10 of 4 0.10Down
Salivary gland12 ± 30 of 4 0.14Down
Crop10 ± 21 of 4 0.10Down
Midgut3 ± 10 of 4 0.00Down
Tubule16 ± 32 of 4 0.20Down
Hindgut30 ± 24 of 4 0.40Down
Heart496 ± 134 of 4 5.85Up
Fat body1424 ± 904 of 416.77Up
Ovary1 ± 00 of 4 0.00Down
Testis3 ± 11 of 4 0.00Down
Male accessory glands1 ± 00 of 4 0.00Down
Virgin spermatheca1536 ± 744 of 418.09Up
Mated spermatheca1240 ± 734 of 414.60Up
Adult carcass557 ± 274 of 4 6.60Up
Larval CNS3 ± 10 of 4 0.04Down
Larval Salivary gland100 ± 124 of 4 1.18None
Larval midgut381 ± 334 of 4 4.50Up
Larval tubule8 ± 20 of 4 0.10Down
Larval hindgut38 ± 44 of 4 0.45Down
Larval fat body445 ± 844 of 4 5.20Up
Larval trachea43 ± 332 of 4 0.51None
Larval carcass71 ± 104 of 4 0.85None
S2 cells (growing)2 ± 10 of 4 0.03Down
Whole fly84 ± 134 of 4

Looking for FBgn0015570. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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