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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0015571 through 18771 annotations produced 1 hits



fragment B (alpha-Est3):

Annotation Number : CG1257
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015571
Gbrowse : chr3R:3364693-3367349 (-) // 100.0 //
Probeset : 1625354_at
Accessions : protein= NP_001163540; /// NP_524267;, nucleotide= NM_001170069; /// NM_079543;
Interpro : 0004091 // carboxylesterase activity // inferred from sequence or structural similarity /// 0004091 // carboxylesterase
FlyMine data for FBgn0015571.
BDGP gene expression has embryonic in situ data for alpha-Est3: 8 pix of staining in 1 body parts.
Homophila reports that CG1257 is a close match (9e-14) to human gene AITD3;TG (NP_003226), a gene associated with Goiter, adolescent multinodular (1);Goiter, nonendemic, simple (3);Hypothyroidism, hereditary congenital (3);{Autoimmune thyroid disease, susceptibility to 3}, 608175 (3).
VDRC has 3 RNAi stocks for FBgn0015571 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain25 ± 14 of 4 0.20Down
Head71 ± 34 of 4 0.50Down
Eye64 ± 44 of 4 0.41Down
Thoracicoabdominal ganglion42 ± 04 of 4 0.30Down
Salivary gland406 ± 154 of 4 2.57Up
Crop225 ± 54 of 4 1.40Up
Midgut259 ± 44 of 4 1.60Up
Tubule1174 ± 354 of 4 7.40Up
Hindgut300 ± 34 of 4 1.90Up
Heart328 ± 154 of 4 2.07Up
Fat body280 ± 334 of 4 1.77Up
Ovary76 ± 24 of 4 0.50Down
Testis791 ± 124 of 4 5.00Up
Male accessory glands109 ± 64 of 4 0.70Down
Virgin spermatheca132 ± 24 of 4 0.84Down
Mated spermatheca112 ± 34 of 4 0.71Down
Adult carcass250 ± 184 of 4 1.60Up
Larval CNS22 ± 04 of 4 0.14Down
Larval Salivary gland92 ± 114 of 4 0.58Down
Larval midgut541 ± 44 of 4 3.42Up
Larval tubule642 ± 434 of 4 4.10Up
Larval hindgut266 ± 234 of 4 1.68Up
Larval fat body171 ± 104 of 4 1.10None
Larval trachea87 ± 54 of 4 0.55Down
Larval carcass159 ± 124 of 4 1.01None
S2 cells (growing)51 ± 14 of 4 0.32Down
Whole fly158 ± 54 of 4

Looking for FBgn0015571. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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