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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0015799 through 18771 annotations produced 1 hits

Retinoblastoma-family protein (Rbf):

Annotation Number : CG7413
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015799
Gbrowse : chrX:691120-695490 (-) // 100.0 //
Probeset : 1623479_at
Accessions : protein= NP_525036;, nucleotide= NM_080297;
Pathway : 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634
Interpro : 0003677 // DNA binding // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotati
FlyMine data for FBgn0015799.
BDGP gene expression has embryonic in situ data for Rbf: 10 pix of staining in 11 body parts.
Homophila reports that CG7413 is a close match (2e-33) to human gene RB1 (NP_000312), a gene associated with Bladder cancer, 109800 (3);Osteosarcoma, 259500 (2);Pinealoma with bilateral retinoblastoma (2);Retinoblastoma (3).
BioGrid reports that CG7413 interacts with CG14026 CG2411 CG9096 CG9096 CG1772 CG1772 CG1772 CG1772 CG1772 CG1772 CG3938 CG4654 CG4654 CG6376 CG6376 CG6376 CG6376 CG5072 CG5072 CG5072 CG4654 CG4654 CG6376 CG6376 CG6376 CG6376 .
TRiP has 2 RNAi stocks for FBgn0015799 available for purchase.
VDRC has 1 RNAi stocks for FBgn0015799 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain107 34 of 4 0.80Down
Head45 54 of 4 0.30Down
Eye35 24 of 4 0.25Down
Thoracicoabdominal ganglion61 54 of 4 0.40Down
Salivary gland80 54 of 4 0.58Down
Crop33 31 of 4 0.20Down
Midgut46 34 of 4 0.30Down
Tubule51 34 of 4 0.40Down
Hindgut40 04 of 4 0.30Down
Heart30 34 of 4 0.21Down
Fat body41 44 of 4 0.29Down
Ovary381 74 of 4 2.70Up
Testis83 34 of 4 0.60Down
Male accessory glands45 24 of 4 0.30Down
Virgin spermatheca33 12 of 4 0.24Down
Mated spermatheca37 44 of 4 0.27Down
Adult carcass50 63 of 4 0.40Down
Larval CNS158 94 of 4 1.13None
Larval Salivary gland136 44 of 4 0.97None
Larval midgut57 14 of 4 0.41Down
Larval tubule28 24 of 4 0.20Down
Larval hindgut78 54 of 4 0.56Down
Larval fat body32 63 of 4 0.20Down
Larval trachea91 54 of 4 0.65Down
Larval carcass82 74 of 4 0.59Down
S2 cells (growing)144 44 of 4 1.03None
Whole fly140 84 of 4

Looking for FBgn0015799. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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