FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0015808 through 18771 annotations produced 2 hits

/// sterol carrier protein X-related thiolase (CG17597 /// ScpX):

Annotation Number : CG17597
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015808 /// FBgn0032715
Gbrowse : chr2L:18831720-18832999 (+) // 63.13 // /// chr2L:18829005-18831141 (-) // 100.0 //
Probeset : 1628744_s_at
Accessions : protein= NP_524715; /// NP_609912;, nucleotide= NM_079976; /// NM_136068;
Pathway : 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from se
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activi
FlyMine data for FBgn0015808 /// FBgn0032715.
Homophila reports that CG17597 is a close match (1e-103) to human gene SCP2 (NP_001007099), a gene associated with Leukoencephalopathy with dystonia and motor neuropathy (3).
BioGrid reports that CG17597 interacts with CG6864 .

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	107 ± 5	4 of 4	0.30	Down
Head	308 ± 13	4 of 4	1.00	None
Eye	172 ± 12	4 of 4	0.55	Down
Thoracicoabdominal ganglion	103 ± 1	4 of 4	0.30	Down
Salivary gland	303 ± 10	4 of 4	0.97	None
Crop	765 ± 10	4 of 4	2.50	Up
Midgut	1497 ± 19	4 of 4	4.80	Up
Tubule	1249 ± 42	4 of 4	4.00	Up
Hindgut	573 ± 5	4 of 4	1.80	Up
Heart	877 ± 37	4 of 4	2.82	Up
Fat body	892 ± 123	4 of 4	2.87	Up
Ovary	178 ± 3	4 of 4	0.60	Down
Testis	73 ± 1	3 of 4	0.20	Down
Male accessory glands	225 ± 5	4 of 4	0.70	Down
Virgin spermatheca	382 ± 22	4 of 4	1.23	None
Mated spermatheca	316 ± 24	4 of 4	1.02	None
Adult carcass	708 ± 15	4 of 4	2.30	Up
Larval CNS	98 ± 17	4 of 4	0.32	Down
Larval Salivary gland	269 ± 20	4 of 4	0.86	None
Larval midgut	1666 ± 68	4 of 4	5.35	Up
Larval tubule	1821 ± 65	4 of 4	5.90	Up
Larval hindgut	322 ± 25	4 of 4	1.04	None
Larval fat body	1485 ± 163	4 of 4	4.80	Up
Larval trachea	300 ± 7	4 of 4	0.96	None
Larval carcass	227 ± 10	4 of 4	0.73	Down
S2 cells (growing)	226 ± 5	4 of 4	0.73	Down
Whole fly	311 ± 19	4 of 4

sterol carrier protein X-related thiolase (ScpX):

Annotation Number : CG17320
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015808
Gbrowse : chr2L:18831215-18833639 (+) // 100.0 // /// chr2L:18829097-18830462 (-) // 58.06 //
Probeset : 1630643_at
Accessions : protein= NP_524715;, nucleotide= NM_079976;
Pathway : 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from se
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from ph
FlyMine data for FBgn0015808.
BDGP gene expression has embryonic in situ data for ScpX: 16 pix of staining in 9 body parts.
Homophila reports that CG17320 is a close match (5e-12) to human gene HSD17B4 (NP_000405), a gene associated with D-bifunctional protein deficiency, 261515 (3).
BioGrid reports that CG17320 interacts with CG32486 .
VDRC has 3 RNAi stocks for FBgn0015808 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	138 ± 6	4 of 4	0.60	Down
Head	423 ± 16	4 of 4	1.70	Up
Eye	223 ± 8	4 of 4	0.92	None
Thoracicoabdominal ganglion	155 ± 2	4 of 4	0.60	Down
Salivary gland	266 ± 9	4 of 4	1.09	None
Crop	993 ± 22	4 of 4	4.10	Up
Midgut	385 ± 6	4 of 4	1.60	Up
Tubule	711 ± 37	4 of 4	2.90	Up
Hindgut	418 ± 5	4 of 4	1.70	Up
Heart	608 ± 20	4 of 4	2.50	Up
Fat body	1045 ± 77	4 of 4	4.29	Up
Ovary	243 ± 6	4 of 4	1.00	None
Testis	123 ± 7	4 of 4	0.50	Down
Male accessory glands	184 ± 7	4 of 4	0.80	Down
Virgin spermatheca	2304 ± 97	4 of 4	9.46	Up
Mated spermatheca	1660 ± 132	4 of 4	6.81	Up
Adult carcass	606 ± 16	4 of 4	2.50	Up
Larval CNS	201 ± 9	4 of 4	0.83	Down
Larval Salivary gland	253 ± 7	4 of 4	1.04	None
Larval midgut	664 ± 14	4 of 4	2.73	Up
Larval tubule	434 ± 13	4 of 4	1.80	Up
Larval hindgut	273 ± 15	4 of 4	1.12	None
Larval fat body	1425 ± 158	4 of 4	5.80	Up
Larval trachea	430 ± 6	4 of 4	1.77	Up
Larval carcass	252 ± 12	4 of 4	1.04	None
S2 cells (growing)	283 ± 3	4 of 4	1.16	Up
Whole fly	243 ± 12	4 of 4

Looking for FBgn0015808. 2 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720