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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0016013 through 18771 annotations produced 1 hits

Fumarylacetoacetase (Faa):

Annotation Number : CG14993
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0016013
Gbrowse : chr3L:4072029-4073949 (-) // 100.0 //
Probeset : 1638810_at
Accessions : protein= NP_524830;, nucleotide= NM_080091;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004334 // fumarylacetoacetase activity // infe
FlyMine data for FBgn0016013.
BDGP gene expression has embryonic in situ data for Faa: 17 pix of staining in 3 body parts.
Homophila reports that CG14993 is a close match (1e-144) to human gene FAH (NP_000128), a gene associated with Tyrosinemia, type I (3).
BioGrid reports that CG14993 interacts with CG32772 .
VDRC has 2 RNAi stocks for FBgn0016013 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain13 03 of 4 0.30Down
Head140 74 of 4 3.20Up
Eye75 44 of 4 1.73Up
Thoracicoabdominal ganglion21 21 of 4 0.50Down
Salivary gland26 10 of 4 0.61Down
Crop17 20 of 4 0.40Down
Midgut11 20 of 4 0.30Down
Tubule78 84 of 4 1.80Up
Hindgut23 21 of 4 0.50Down
Heart27 34 of 4 0.62Down
Fat body50 54 of 4 1.15None
Ovary3 10 of 4 0.10Down
Testis23 54 of 4 0.50Down
Male accessory glands27 11 of 4 0.60Down
Virgin spermatheca30 34 of 4 0.69Down
Mated spermatheca34 14 of 4 0.78Down
Adult carcass178 124 of 4 4.10Up
Larval CNS15 00 of 4 0.35Down
Larval Salivary gland9 10 of 4 0.22Down
Larval midgut18 30 of 4 0.43Down
Larval tubule37 31 of 4 0.90None
Larval hindgut53 14 of 4 1.22Up
Larval fat body19 30 of 4 0.40Down
Larval trachea18 63 of 4 0.42Down
Larval carcass302 704 of 4 6.95Up
S2 cells (growing)8 11 of 4 0.18Down
Whole fly43 14 of 4

Looking for FBgn0016013. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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