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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0016122 through 18771 annotations produced 1 hits



Angiotensin-converting enzyme-related (Acer):

Annotation Number : CG10593
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0016122
Gbrowse : chr2L:8521898-8524991 (+) // 100.0 //
Probeset : 1640031_at
Accessions : protein= NP_477195;, nucleotide= NM_057847;
Pathway : 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from elect
Interpro : 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred f
FlyMine data for FBgn0016122.
BDGP gene expression has embryonic in situ data for Acer: 22 pix of staining in 6 body parts.
Homophila reports that CG10593 is a close match (2e-133) to human gene ACE;ACE1;DCP1 (NP_000780), a gene associated with Renal tubular dysgenesis, 267430 (3);[Angiotensin I-converting enzyme, benign serum increase] (3);{Alzheimer disease, susceptibility to}, 104300 (3);{Diabetic nephropathy, susceptibility to}, 603933 (3);{Myocardial infarction, susceptibility to} (3);{SARS, progression of} (3).
BioGrid reports that CG10593 interacts with CG5844 CG32654 .
VDRC has 1 RNAi stocks for FBgn0016122 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain96 ± 44 of 4 0.20Down
Head1282 ± 754 of 4 2.50Up
Eye556 ± 984 of 4 1.09None
Thoracicoabdominal ganglion112 ± 34 of 4 0.20Down
Salivary gland17 ± 70 of 4 0.03Down
Crop417 ± 244 of 4 0.80Down
Midgut58 ± 34 of 4 0.10Down
Tubule35 ± 52 of 4 0.10Down
Hindgut309 ± 94 of 4 0.60Down
Heart1453 ± 864 of 4 2.85Up
Fat body2618 ± 3554 of 4 5.14Up
Ovary431 ± 194 of 4 0.80Down
Testis920 ± 364 of 4 1.80Up
Male accessory glands77 ± 94 of 4 0.20Down
Virgin spermatheca1522 ± 1324 of 4 2.99Up
Mated spermatheca2104 ± 1504 of 4 4.13Up
Adult carcass1529 ± 374 of 4 3.00Up
Larval CNS40 ± 114 of 4 0.08Down
Larval Salivary gland35 ± 52 of 4 0.07Down
Larval midgut31 ± 21 of 4 0.06Down
Larval tubule67 ± 34 of 4 0.10Down
Larval hindgut419 ± 74 of 4 0.82Down
Larval fat body586 ± 224 of 4 1.20Up
Larval trachea52 ± 104 of 4 0.10Down
Larval carcass332 ± 574 of 4 0.65None
S2 cells (growing)39 ± 24 of 4 0.08Down
Whole fly509 ± 114 of 4

Looking for FBgn0016122. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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