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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0016696 through 18771 annotations produced 2 hits


PITSLRE (Pitslre):

Annotation Number : CG4268
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0016696
Gbrowse : chr3L:20764636-20766060 (+) // 100.0 //
Probeset : 1629503_s_at
Accessions : protein= NP_649251; /// NP_730563; /// NP_730564; /// NP_730565;, nucleotide= NM_140994; /// NM_168869; /// NM_168870; /// NM_168871;
Pathway : 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0016696.
BDGP gene expression has embryonic in situ data for Pitslre: 15 pix of staining in 21 body parts.
Homophila reports that CG4268 is a close match (4e-12) to human gene JAK2 (NP_004963), a gene associated with Leukemia, acute myelogenous, 601626 (3);Myelofibrosis, idiopathic, 254450 (3);Myeloproliferative disorder with erythrocytosis (3);Polycythemia vera, 263300 (3);Thrombocythemia, essential, 187950 (3);{Budd-Chiari syndrome}, 600880 (3).
TRiP has 1 RNAi stocks for FBgn0016696 available for purchase.
VDRC has 2 RNAi stocks for FBgn0016696 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain49 ± 64 of 4 3.60Up
Head17 ± 22 of 4 1.20None
Eye16 ± 44 of 4 1.22None
Thoracicoabdominal ganglion23 ± 64 of 4 1.70None
Salivary gland32 ± 12 of 4 2.34Up
Crop28 ± 54 of 4 2.10None
Midgut16 ± 33 of 4 1.20None
Tubule8 ± 11 of 4 0.60Down
Hindgut19 ± 23 of 4 1.40None
Heart16 ± 14 of 4 1.22None
Fat body19 ± 61 of 4 1.40None
Ovary7 ± 11 of 4 0.50Down
Testis8 ± 01 of 4 0.60Down
Male accessory glands26 ± 14 of 4 1.90Up
Virgin spermatheca8 ± 11 of 4 0.60Down
Mated spermatheca16 ± 00 of 4 1.17None
Adult carcass17 ± 13 of 4 1.30None
Larval CNS12 ± 44 of 4 0.89None
Larval Salivary gland15 ± 11 of 4 1.11None
Larval midgut14 ± 04 of 4 1.06None
Larval tubule18 ± 04 of 4 1.30Up
Larval hindgut12 ± 12 of 4 0.93None
Larval fat body55 ± 74 of 4 4.00Up
Larval trachea14 ± 54 of 4 1.02None
Larval carcass10 ± 20 of 4 0.74None
S2 cells (growing)20 ± 04 of 4 1.52Up
Whole fly13 ± 03 of 4


PITSLRE (Pitslre):

Annotation Number : CG4268
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0016696
Gbrowse : chr3L:20764636-20770037 (+) // 100.0 //
Probeset : 1633625_s_at
Accessions : protein= NP_649251; /// NP_730563; /// NP_730564; /// NP_730565;, nucleotide= NM_140994; /// NM_168869; /// NM_168870; /// NM_168871;
Pathway : 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0016696.
BDGP gene expression has embryonic in situ data for Pitslre: 15 pix of staining in 21 body parts.
Homophila reports that CG4268 is a close match (4e-12) to human gene JAK2 (NP_004963), a gene associated with Leukemia, acute myelogenous, 601626 (3);Myelofibrosis, idiopathic, 254450 (3);Myeloproliferative disorder with erythrocytosis (3);Polycythemia vera, 263300 (3);Thrombocythemia, essential, 187950 (3);{Budd-Chiari syndrome}, 600880 (3).
TRiP has 1 RNAi stocks for FBgn0016696 available for purchase.
VDRC has 2 RNAi stocks for FBgn0016696 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain972 ± 514 of 4 3.80Up
Head200 ± 84 of 4 0.80Down
Eye229 ± 44 of 4 0.89None
Thoracicoabdominal ganglion516 ± 184 of 4 2.00Up
Salivary gland232 ± 104 of 4 0.90None
Crop213 ± 54 of 4 0.80Down
Midgut151 ± 74 of 4 0.60Down
Tubule185 ± 14 of 4 0.70Down
Hindgut199 ± 74 of 4 0.80Down
Heart137 ± 44 of 4 0.53Down
Fat body168 ± 114 of 4 0.65Down
Ovary571 ± 154 of 4 2.20Up
Testis57 ± 24 of 4 0.20Down
Male accessory glands291 ± 104 of 4 1.10None
Virgin spermatheca177 ± 114 of 4 0.69Down
Mated spermatheca190 ± 144 of 4 0.73Down
Adult carcass194 ± 104 of 4 0.80Down
Larval CNS351 ± 204 of 4 1.36Up
Larval Salivary gland166 ± 124 of 4 0.64Down
Larval midgut87 ± 104 of 4 0.34Down
Larval tubule175 ± 14 of 4 0.70Down
Larval hindgut141 ± 114 of 4 0.55Down
Larval fat body304 ± 144 of 4 1.20Up
Larval trachea149 ± 94 of 4 0.58Down
Larval carcass135 ± 24 of 4 0.53Down
S2 cells (growing)141 ± 24 of 4 0.55Down
Whole fly258 ± 114 of 4

Looking for FBgn0016696. 2 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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