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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0016917 through 18771 annotations produced 1 hits

marelle (Stat92E):

Annotation Number : CG4257
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0016917
Gbrowse : chr3R:16361404-16378034 (-) // 100.0 //
Probeset : 1635827_s_at
Accessions : protein= NP_001014643; /// NP_732516; /// NP_732517; /// NP_996242; /// NP_996243;, nucleotide= NM_001014643; /// NM_169899; /// NM_169900; /// NM_206520; /// NM_206521;
Pathway : DNA-dependent // inferred from electronic annotation /// 0006952 // defense response // non-traceable author statement
Interpro : open tracheal system // traceable author statement /// 0007442 // hindgut morphogenesis // inferred from mutant phenoty
FlyMine data for FBgn0016917.
Homophila reports that CG4257 is a close match (2e-34) to human gene STAT3;APRF (NP_998827), a gene associated with Hyperimmunoglobulin E recurrent infection syndrome, 147060 (3).
BioGrid reports that CG4257 interacts with CG4697 CG8068 CG8068 CG5490 CG10079 CG1389 CG1389 CG1594 CG1594 CG1594 CG1594 CG1594 CG1594 CG1594 CG1594 CG1594 CG1594 CG1594 CG1594 CG5993 CG4354 CG14226 CG14226 CG5072 CG10498 .
TRiP has 4 RNAi stocks for FBgn0016917 available for purchase.
VDRC has 3 RNAi stocks for FBgn0016917 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain444 94 of 4 0.80Down
Head849 324 of 4 1.60Up
Eye351 234 of 4 0.67Down
Thoracicoabdominal ganglion272 84 of 4 0.50Down
Salivary gland354 94 of 4 0.68Down
Crop728 74 of 4 1.40Up
Midgut782 114 of 4 1.50Up
Tubule1329 624 of 4 2.50Up
Hindgut678 144 of 4 1.30Up
Heart808 284 of 4 1.54Up
Fat body1964 1704 of 4 3.75Up
Ovary865 64 of 4 1.70Up
Testis80 34 of 4 0.20Down
Male accessory glands295 184 of 4 0.60Down
Virgin spermatheca3309 894 of 4 6.32Up
Mated spermatheca3236 1814 of 4 6.18Up
Adult carcass895 574 of 4 1.70Up
Larval CNS252 404 of 4 0.48Down
Larval Salivary gland511 294 of 4 0.98None
Larval midgut621 454 of 4 1.19None
Larval tubule581 154 of 4 1.10Up
Larval hindgut535 94 of 4 1.02None
Larval fat body2217 2184 of 4 4.20Up
Larval trachea345 384 of 4 0.66Down
Larval carcass518 164 of 4 0.99None
S2 cells (growing)623 124 of 4 1.19Up
Whole fly523 124 of 4

Looking for FBgn0016917. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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