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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0019948 through 18771 annotations produced 2 hits



Peptidyl gycine alpha hydroxylating monooxygenase (Phm):

Annotation Number : CG3832
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0019948
Gbrowse : chr2R:19872749-19875990 (-) // 100.0 //
Probeset : 1623430_at
Accessions : protein= NP_477225; /// NP_726394;, nucleotide= NM_057877; /// NM_166644;
Pathway : 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electron
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred f
FlyMine data for FBgn0019948.
BDGP gene expression has embryonic in situ data for Phm: 15 pix of staining in 6 body parts.
Homophila reports that CG3832 is a close match (7e-11) to human gene DBH (NP_000778), a gene associated with Dopamine beta-hydroxylase deficiency, 223360 (3);Parkinson disease, resistance to, 168600 (3);[Dopamine-beta-hydroxylase activity levels, plasma] (3).
BioGrid reports that CG3832 interacts with CG9986 .
VDRC has 3 RNAi stocks for FBgn0019948 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain94 ± 34 of 4 2.30Up
Head70 ± 24 of 4 1.80Up
Eye147 ± 54 of 4 3.67Up
Thoracicoabdominal ganglion85 ± 34 of 4 2.10Up
Salivary gland75 ± 124 of 4 1.89None
Crop87 ± 64 of 4 2.20Up
Midgut27 ± 24 of 4 0.70Down
Tubule58 ± 24 of 4 1.50Up
Hindgut74 ± 14 of 4 1.90Up
Heart123 ± 74 of 4 3.09Up
Fat body54 ± 64 of 4 1.35Up
Ovary42 ± 14 of 4 1.10None
Testis16 ± 14 of 4 0.40Down
Male accessory glands92 ± 74 of 4 2.30Up
Virgin spermatheca122 ± 54 of 4 3.05Up
Mated spermatheca126 ± 44 of 4 3.16Up
Adult carcass48 ± 24 of 4 1.20None
Larval CNS81 ± 114 of 4 2.02Up
Larval Salivary gland115 ± 44 of 4 2.88Up
Larval midgut29 ± 24 of 4 0.74Down
Larval tubule34 ± 14 of 4 0.90None
Larval hindgut46 ± 34 of 4 1.15None
Larval fat body69 ± 64 of 4 1.70Up
Larval trachea121 ± 54 of 4 3.03Up
Larval carcass52 ± 24 of 4 1.31Up
S2 cells (growing)205 ± 64 of 4 5.13Up
Whole fly40 ± 24 of 4



Peptidyl gycine alpha hydroxylating monooxygenase (Phm):

Annotation Number : CG3832
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0019948
Gbrowse : chr2R:19872854-19875990 (-) // 100.0 //
Probeset : 1631675_a_at
Accessions : protein= NP_477225; /// NP_726394;, nucleotide= NM_057877; /// NM_166644;
Pathway : 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electron
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred f
FlyMine data for FBgn0019948.
BDGP gene expression has embryonic in situ data for Phm: 15 pix of staining in 6 body parts.
Homophila reports that CG3832 is a close match (7e-11) to human gene DBH (NP_000778), a gene associated with Dopamine beta-hydroxylase deficiency, 223360 (3);Parkinson disease, resistance to, 168600 (3);[Dopamine-beta-hydroxylase activity levels, plasma] (3).
BioGrid reports that CG3832 interacts with CG9986 .
VDRC has 3 RNAi stocks for FBgn0019948 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1059 ± 154 of 4 3.10Up
Head1159 ± 344 of 4 3.40Up
Eye2451 ± 274 of 4 7.29Up
Thoracicoabdominal ganglion893 ± 284 of 4 2.70Up
Salivary gland3686 ± 754 of 410.96Up
Crop762 ± 284 of 4 2.30Up
Midgut372 ± 154 of 4 1.10None
Tubule456 ± 314 of 4 1.40Up
Hindgut877 ± 144 of 4 2.60Up
Heart818 ± 264 of 4 2.43Up
Fat body878 ± 824 of 4 2.61Up
Ovary198 ± 34 of 4 0.60Down
Testis297 ± 44 of 4 0.90None
Male accessory glands1611 ± 494 of 4 4.80Up
Virgin spermatheca972 ± 244 of 4 2.89Up
Mated spermatheca903 ± 394 of 4 2.69Up
Adult carcass671 ± 314 of 4 2.00Up
Larval CNS524 ± 294 of 4 1.56Up
Larval Salivary gland1620 ± 554 of 4 4.82Up
Larval midgut274 ± 84 of 4 0.82Down
Larval tubule392 ± 224 of 4 1.20None
Larval hindgut556 ± 154 of 4 1.65Up
Larval fat body968 ± 754 of 4 2.90Up
Larval trachea724 ± 634 of 4 2.15Up
Larval carcass476 ± 94 of 4 1.42Up
S2 cells (growing)1330 ± 384 of 4 3.95Up
Whole fly336 ± 184 of 4

Looking for FBgn0019948. 2 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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