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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0019972 through 18771 annotations produced 1 hits

Ice (Ice):

Annotation Number : CG7788
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0019972
Gbrowse : chr3R:25625374-25627307 (+) // 100.0 //
Probeset : 1634668_at
Accessions : protein= NP_524551;, nucleotide= NM_079827;
Pathway : 0008303 // caspase complex // non-traceable author statement
Interpro : 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase
FlyMine data for FBgn0019972.
BDGP gene expression has embryonic in situ data for Ice: 13 pix of staining in 10 body parts.
Homophila reports that CG7788 is a close match (2e-34) to human gene ALPS2;CASP10;MCH4 (NP_116756), a gene associated with Autoimmune lymphoproliferative syndrome, type II, 603909 (3);Gastric cancer, somatic, 137215 (3);Non-Hodgkin lymphoma, somatic, 605027 (3).
BioGrid reports that CG7788 interacts with CG4319 CG4319 CG4319 CG4319 CG6829 CG8091 CG7788 .
TRiP has 1 RNAi stocks for FBgn0019972 available for purchase.
VDRC has 2 RNAi stocks for FBgn0019972 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain120 34 of 4 0.40Down
Head165 64 of 4 0.60Down
Eye106 34 of 4 0.36Down
Thoracicoabdominal ganglion92 44 of 4 0.30Down
Salivary gland116 64 of 4 0.39Down
Crop303 54 of 4 1.00None
Midgut417 164 of 4 1.40Up
Tubule332 154 of 4 1.10Up
Hindgut239 34 of 4 0.80Down
Heart242 144 of 4 0.81Down
Fat body480 584 of 4 1.60Up
Ovary552 84 of 4 1.80Up
Testis48 24 of 4 0.20Down
Male accessory glands77 44 of 4 0.30Down
Virgin spermatheca347 264 of 4 1.16None
Mated spermatheca278 194 of 4 0.93None
Adult carcass237 74 of 4 0.80Down
Larval CNS681 1514 of 4 2.27Up
Larval Salivary gland222 74 of 4 0.74Down
Larval midgut938 1284 of 4 3.13Up
Larval tubule952 174 of 4 3.20Up
Larval hindgut566 724 of 4 1.89Up
Larval fat body529 474 of 4 1.80Up
Larval trachea462 224 of 4 1.54Up
Larval carcass981 574 of 4 3.27Up
S2 cells (growing)668 244 of 4 2.23Up
Whole fly300 64 of 4

Looking for FBgn0019972. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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