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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0021796 through 18771 annotations produced 1 hits

Target of rapamycin (Tor):

Annotation Number : CG5092
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0021796
Gbrowse : chr2L:13004785-13013197 (+) // 99.95 //
Probeset : 1641510_at
Accessions : protein= NP_524891;, nucleotide= NM_080152;
Interpro : "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-trac
FlyMine data for FBgn0021796.
Homophila reports that CG5092 is a close match (5e-47) to human gene AT1;ATA;ATM (NP_000042), a gene associated with Ataxia-telangiectasia, 208900 (3);Lymphoma, B-cell non-Hodgkin, somatic (3);Lymphoma, mantle cell (3);T-cell prolymphocytic leukemia, sporadic (3);{Breast cancer, susceptibility to}, 114480 (3).
BioGrid reports that CG5092 interacts with CG10798 CG3938 CG4141 CG10539 CG5671 CG5671 CG6147 CG6147 .
TRiP has 3 RNAi stocks for FBgn0021796 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain151 34 of 4 1.10Up
Head101 34 of 4 0.70Down
Eye129 44 of 4 0.95None
Thoracicoabdominal ganglion150 34 of 4 1.10Up
Salivary gland166 174 of 4 1.23None
Crop184 34 of 4 1.40Up
Midgut116 44 of 4 0.90Down
Tubule153 44 of 4 1.10Up
Hindgut238 64 of 4 1.80Up
Heart167 64 of 4 1.23Up
Fat body110 94 of 4 0.81Down
Ovary273 34 of 4 2.00Up
Testis40 24 of 4 0.30Down
Male accessory glands76 44 of 4 0.60Down
Virgin spermatheca215 34 of 4 1.59Up
Mated spermatheca247 54 of 4 1.82Up
Adult carcass139 24 of 4 1.00None
Larval CNS260 184 of 4 1.91Up
Larval Salivary gland206 164 of 4 1.52Up
Larval midgut105 54 of 4 0.77Down
Larval tubule135 24 of 4 1.00None
Larval hindgut116 44 of 4 0.86Down
Larval fat body200 154 of 4 1.50Up
Larval trachea194 154 of 4 1.43Up
Larval carcass124 64 of 4 0.91None
S2 cells (growing)197 44 of 4 1.45Up
Whole fly136 34 of 4

Looking for FBgn0021796. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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