FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0022355 through 18771 annotations produced 3 hits

Transferrin 1 (Tsf1):

Annotation Number : CG6186
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0022355
Gbrowse : chrX:18281964-18284377 (+) // 100.0 //
Probeset : 1632430_at
Accessions : protein= NP_523401;, nucleotide= NM_078677;
Pathway : 0005576 // extracellular region // inferred from electronic annotation
Interpro : 0005381 // iron ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0005381 //
FlyMine data for FBgn0022355.
Homophila reports that CG6186 is a close match (4e-22) to human gene TF (NP_001054), a gene associated with Atransferrinemia, 209300 (3);{Iron deficiency anemia, susceptibility to} (3).
VDRC has 2 RNAi stocks for FBgn0022355 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	1887 ± 27	4 of 4	2.20	Up
Head	2996 ± 247	4 of 4	3.50	Up
Eye	2556 ± 245	4 of 4	3.03	Up
Thoracicoabdominal ganglion	3001 ± 84	4 of 4	3.60	Up
Salivary gland	352 ± 34	4 of 4	0.42	Down
Crop	155 ± 28	4 of 4	0.20	Down
Midgut	111 ± 22	4 of 4	0.10	Down
Tubule	179 ± 33	4 of 4	0.20	Down
Hindgut	468 ± 41	4 of 4	0.60	Down
Heart	2156 ± 362	4 of 4	2.55	Up
Fat body	2676 ± 166	4 of 4	3.17	Up
Ovary	36 ± 6	4 of 4	0.00	Down
Testis	370 ± 26	4 of 4	0.40	Down
Male accessory glands	43 ± 6	4 of 4	0.10	Down
Virgin spermatheca	3155 ± 123	4 of 4	3.74	Up
Mated spermatheca	1630 ± 375	4 of 4	1.93	None
Adult carcass	3389 ± 183	4 of 4	4.00	Up
Larval CNS	364 ± 65	4 of 4	0.43	Down
Larval Salivary gland	207 ± 12	4 of 4	0.25	Down
Larval midgut	116 ± 3	4 of 4	0.14	Down
Larval tubule	11 ± 1	0 of 4	0.00	Down
Larval hindgut	722 ± 28	4 of 4	0.86	None
Larval fat body	1059 ± 182	4 of 4	1.30	None
Larval trachea	5074 ± 177	4 of 4	6.01	Up
Larval carcass	832 ± 140	4 of 4	0.99	None
S2 cells (growing)	69 ± 7	4 of 4	0.08	Down
Whole fly	844 ± 95	4 of 4

Transferrin 1 (Tsf1):

Annotation Number : CG6186
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0022355
Gbrowse : chrX:18281954-18282635 (+) // 100.0 //
Probeset : 1640934_at
Accessions : protein= NP_523401;, nucleotide= NM_078677;
Pathway : 0005576 // extracellular region // inferred from electronic annotation
Interpro : 0005381 // iron ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0005381 //
FlyMine data for FBgn0022355.
Homophila reports that CG6186 is a close match (4e-22) to human gene TF (NP_001054), a gene associated with Atransferrinemia, 209300 (3);{Iron deficiency anemia, susceptibility to} (3).
VDRC has 2 RNAi stocks for FBgn0022355 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	6 ± 1	1 of 4	5.50	Up
Head	5 ± 1	1 of 4	4.80	Up
Eye	4 ± 0	1 of 4	3.91	Up
Thoracicoabdominal ganglion	3 ± 1	0 of 4	2.80	None
Salivary gland	5 ± 1	0 of 4	4.89	Up
Crop	3 ± 1	0 of 4	2.90	None
Midgut	4 ± 1	0 of 4	3.60	None
Tubule	5 ± 0	0 of 4	5.00	Up
Hindgut	2 ± 1	0 of 4	2.60	None
Heart	2 ± 0	0 of 4	2.66	None
Fat body	4 ± 3	2 of 4	3.77	None
Ovary	2 ± 0	1 of 4	1.90	None
Testis	1 ± 0	0 of 4	1.30	None
Male accessory glands	3 ± 0	0 of 4	3.00	None
Virgin spermatheca	1 ± 0	0 of 4	1.16	None
Mated spermatheca	3 ± 1	0 of 4	2.95	None
Adult carcass	6 ± 3	1 of 4	6.10	None
Larval CNS	1 ± 1	0 of 4	1.61	None
Larval Salivary gland	1 ± 0	0 of 4	1.20	None
Larval midgut	2 ± 1	1 of 4	2.52	None
Larval tubule	1 ± 0	0 of 4	1.30	None
Larval hindgut	3 ± 0	0 of 4	2.86	None
Larval fat body	2 ± 0	0 of 4	2.40	None
Larval trachea	11 ± 1	4 of 4	10.05	Up
Larval carcass	2 ± 0	0 of 4	2.55	None
S2 cells (growing)	1 ± 0	0 of 4	1.39	None
Whole fly	1 ± 0	0 of 4

Transferrin 1 (Tsf1):

Annotation Number : CG6186
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0022355
Gbrowse : chrX:18281954-18282635 (+) // 100.0 //
Probeset : 1639442_a_at
Accessions : protein= NP_523401;, nucleotide= NM_078677;
Pathway : 0005576 // extracellular region // inferred from electronic annotation
Interpro : 0005381 // iron ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0005381 //
FlyMine data for FBgn0022355.
Homophila reports that CG6186 is a close match (4e-22) to human gene TF (NP_001054), a gene associated with Atransferrinemia, 209300 (3);{Iron deficiency anemia, susceptibility to} (3).
VDRC has 2 RNAi stocks for FBgn0022355 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	595 ± 11	4 of 4	3.90	Up
Head	1015 ± 69	4 of 4	6.60	Up
Eye	287 ± 30	4 of 4	1.86	None
Thoracicoabdominal ganglion	477 ± 20	4 of 4	3.10	Up
Salivary gland	70 ± 5	4 of 4	0.46	None
Crop	30 ± 5	2 of 4	0.20	None
Midgut	20 ± 4	1 of 4	0.10	None
Tubule	20 ± 1	1 of 4	0.10	Down
Hindgut	117 ± 21	4 of 4	0.80	None
Heart	310 ± 97	4 of 4	2.01	None
Fat body	428 ± 148	4 of 4	2.78	Up
Ovary	9 ± 1	0 of 4	0.10	Down
Testis	58 ± 5	4 of 4	0.40	None
Male accessory glands	6 ± 2	0 of 4	0.00	Down
Virgin spermatheca	71 ± 8	4 of 4	0.46	None
Mated spermatheca	35 ± 6	3 of 4	0.23	None
Adult carcass	772 ± 78	4 of 4	5.00	Up
Larval CNS	58 ± 16	4 of 4	0.38	None
Larval Salivary gland	24 ± 2	2 of 4	0.16	None
Larval midgut	14 ± 2	0 of 4	0.09	None
Larval tubule	6 ± 1	0 of 4	0.00	Down
Larval hindgut	87 ± 5	4 of 4	0.56	None
Larval fat body	263 ± 45	4 of 4	1.70	None
Larval trachea	1876 ± 347	4 of 4	12.16	Up
Larval carcass	114 ± 15	4 of 4	0.74	None
S2 cells (growing)	38 ± 4	4 of 4	0.25	None
Whole fly	154 ± 44	4 of 4

Looking for FBgn0022355. 3 entries matched from 18771, in 0 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720