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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0023081 through 18771 annotations produced 1 hits

Genghis Kahn (gek):

Annotation Number : CG4012
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0023081
Gbrowse : chr2R:19979599-19986157 (-) // 100.0 //
Probeset : 1640589_at
Accessions : protein= NP_523837;, nucleotide= NM_079113;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0023081.
Homophila reports that CG4012 is a close match (2e-11) to human gene SRK;STD;ZAP70 (NP_001070), a gene associated with Selective T-cell defect (3).
TRiP has 1 RNAi stocks for FBgn0023081 available for purchase.
VDRC has 2 RNAi stocks for FBgn0023081 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain334 74 of 4 2.00Up
Head210 14 of 4 1.30Up
Eye287 174 of 4 1.71Up
Thoracicoabdominal ganglion389 184 of 4 2.30Up
Salivary gland175 84 of 4 1.05None
Crop339 124 of 4 2.00Up
Midgut88 24 of 4 0.50Down
Tubule165 54 of 4 1.00None
Hindgut174 84 of 4 1.00None
Heart216 44 of 4 1.29Up
Fat body138 114 of 4 0.83Down
Ovary284 84 of 4 1.70Up
Testis57 24 of 4 0.30Down
Male accessory glands125 104 of 4 0.70Down
Virgin spermatheca159 74 of 4 0.95None
Mated spermatheca161 44 of 4 0.96None
Adult carcass209 114 of 4 1.20Up
Larval CNS402 174 of 4 2.40Up
Larval Salivary gland169 24 of 4 1.01None
Larval midgut88 74 of 4 0.53Down
Larval tubule100 34 of 4 0.60Down
Larval hindgut201 24 of 4 1.20Up
Larval fat body117 94 of 4 0.70Down
Larval trachea385 154 of 4 2.29Up
Larval carcass296 74 of 4 1.77Up
S2 cells (growing)283 54 of 4 1.69Up
Whole fly167 64 of 4

Looking for FBgn0023081. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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