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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0023549 through 18771 annotations produced 1 hits

Monocarboxylate transporter 1 (Mct1):

Annotation Number : CG3456
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0023549
Gbrowse : chrX:2088615-2099406 (+) // 100.0 //
Probeset : 1626727_at
Accessions : protein= NP_477334;, nucleotide= NM_057986;
Interpro : 0008028 // monocarboxylic acid transmembrane transporter activity // inferred from sequence or structural similarity
FlyMine data for FBgn0023549.
Homophila reports that CG3456 is a close match (1e-17) to human gene DXS128;SLC16A2;XPCT (NP_006508), a gene associated with Allan-Herndon-Dudley syndrome, 300523 (3).
BioGrid reports that CG3456 interacts with CG8155 .
VDRC has 1 RNAi stocks for FBgn0023549 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain25 24 of 4 0.40Down
Head36 74 of 4 0.60None
Eye13 13 of 4 0.25Down
Thoracicoabdominal ganglion13 10 of 4 0.20Down
Salivary gland1 00 of 4 0.02Down
Crop3 10 of 4 0.10Down
Midgut158 84 of 4 2.80Up
Tubule1 00 of 4 0.00Down
Hindgut47 34 of 4 0.80None
Heart88 54 of 4 1.58Up
Fat body272 94 of 4 4.85Up
Ovary44 14 of 4 0.80None
Testis0 00 of 4 0.00Down
Male accessory glands2 00 of 4 0.00Down
Virgin spermatheca31 44 of 4 0.56None
Mated spermatheca44 24 of 4 0.80None
Adult carcass171 164 of 4 3.00Up
Larval CNS6 10 of 4 0.11Down
Larval Salivary gland16 23 of 4 0.29Down
Larval midgut208 214 of 4 3.71Up
Larval tubule27 14 of 4 0.50Down
Larval hindgut89 54 of 4 1.59Up
Larval fat body1266 704 of 422.60Up
Larval trachea1 20 of 4 0.03Down
Larval carcass57 94 of 4 1.02None
S2 cells (growing)464 124 of 4 8.27Up
Whole fly56 84 of 4

Looking for FBgn0023549. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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