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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0024150 through 18771 annotations produced 1 hits

Adenylyl cyclase 78C (Ac78C):

Annotation Number : CG10564
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0024150
Gbrowse : chr3L:21129552-21164991 (-) // 100.0 //
Probeset : 1628412_at
Accessions : protein= NP_524194;, nucleotide= NM_079470;
Pathway : 0016021 // integral to membrane // inferred from electronic annotation
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004016 // adenylate cyclase activity // inferr
FlyMine data for FBgn0024150.
BDGP gene expression has embryonic in situ data for Ac78C: 45 pix of staining in 7 body parts.
Homophila reports that CG10564 is a close match (9e-19) to human gene CORD6;GUC2D;GUCY2D;LCA1 (NP_000171), a gene associated with Cone-rod dystrophy 6, 601777(3);Leber congenital amaurosis I, 204000 (3).
VDRC has 2 RNAi stocks for FBgn0024150 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain91 34 of 4 5.40Up
Head51 34 of 4 3.00Up
Eye20 14 of 4 1.22None
Thoracicoabdominal ganglion73 34 of 4 4.40Up
Salivary gland6 20 of 4 0.37Down
Crop386 164 of 422.80Up
Midgut15 14 of 4 0.90None
Tubule219 144 of 413.00Up
Hindgut191 94 of 411.30Up
Heart10 32 of 4 0.64None
Fat body5 02 of 4 0.30Down
Ovary5 02 of 4 0.30Down
Testis7 04 of 4 0.50Down
Male accessory glands41 34 of 4 2.50Up
Virgin spermatheca4 21 of 4 0.27Down
Mated spermatheca7 11 of 4 0.45Down
Adult carcass23 14 of 4 1.40Up
Larval CNS197 174 of 411.65Up
Larval Salivary gland13 13 of 4 0.81None
Larval midgut25 14 of 4 1.48Up
Larval tubule170 24 of 410.00Up
Larval hindgut346 204 of 420.50Up
Larval fat body7 10 of 4 0.40Down
Larval trachea32 94 of 4 1.89Up
Larval carcass87 94 of 4 5.16Up
S2 cells (growing)17 04 of 4 1.05None
Whole fly16 14 of 4

Looking for FBgn0024150. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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