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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0024184 through 18771 annotations produced 1 hits

Paired HomeoDomain 1 (unc-4):

Annotation Number : CG6269
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0024184
Gbrowse : chrX:17663415-17674916 (+) // 100.0 //
Probeset : 1636472_at
Accessions : protein= NP_573242;, nucleotide= NM_133014;
Pathway : DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred fr
Interpro : 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic
FlyMine data for FBgn0024184.
Homophila reports that CG6269 is a close match (5e-12) to human gene KTCN;PPCD;PPD;RINX;VSX1 (NP_055403), a gene associated with Corneal dystrophy, hereditary polymorphous posterior, 122000 (3);Craniofacial anomalies, empty sella turcica, corneal endothelial changes, and abnormal retinal and auditory bipolar cells (3);Keratoconus, 148300 (3).
BioGrid reports that CG6269 interacts with CG8384 .
TRiP has 1 RNAi stocks for FBgn0024184 available for purchase.
VDRC has 3 RNAi stocks for FBgn0024184 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain3 10 of 4 1.30None
Head5 00 of 4 2.20None
Eye2 10 of 4 1.09None
Thoracicoabdominal ganglion3 10 of 4 1.20None
Salivary gland9 30 of 4 3.75None
Crop4 10 of 4 1.60None
Midgut3 00 of 4 1.20None
Tubule1 00 of 4 0.40Down
Hindgut2 10 of 4 1.00None
Heart0 00 of 4 0.26None
Fat body3 10 of 4 1.25None
Ovary1 00 of 4 0.50None
Testis0 00 of 4 0.20None
Male accessory glands5 20 of 4 2.00None
Virgin spermatheca3 21 of 4 1.29None
Mated spermatheca3 20 of 4 1.44None
Adult carcass4 10 of 4 1.90None
Larval CNS3 11 of 4 1.21None
Larval Salivary gland1 00 of 4 0.73None
Larval midgut2 10 of 4 0.84None
Larval tubule2 00 of 4 1.00None
Larval hindgut4 10 of 4 1.56None
Larval fat body3 20 of 4 1.30None
Larval trachea1 10 of 4 0.46None
Larval carcass1 00 of 4 0.65None
S2 cells (growing)0 00 of 4 0.35None
Whole fly2 10 of 4

Looking for FBgn0024184. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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