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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0024294 through 18771 annotations produced 1 hits

Serine protease inhibitor 1 (Spn43Aa):

Annotation Number : CG12172
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0024294
Gbrowse : chr2R:3035202-3036757 (+) // 100.0 //
Probeset : 1637939_at
Accessions : protein= NP_524805;, nucleotide= NM_080066;
Interpro : 0004867 // serine-type endopeptidase inhibitor activity // inferred from sequence or structural similarity /// 0004867 /
FlyMine data for FBgn0024294.
BDGP gene expression has embryonic in situ data for Spn43Aa: 41 pix of staining in 11 body parts.
Homophila reports that CG12172 is a close match (3e-18) to human gene C1NH;HAE1;HAE2;SERPING1 (NP_001027466), a gene associated with Angioedema, hereditary, 106100 (3).
VDRC has 3 RNAi stocks for FBgn0024294 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain0 00 of 4 0.00Down
Head0 00 of 4 0.00Down
Eye4 21 of 4 0.26Down
Thoracicoabdominal ganglion0 00 of 4 0.10Down
Salivary gland1 00 of 4 0.08Down
Crop1 00 of 4 0.10Down
Midgut1 00 of 4 0.10Down
Tubule2 00 of 4 0.10Down
Hindgut0 00 of 4 0.00Down
Heart2 10 of 4 0.16Down
Fat body2 00 of 4 0.11Down
Ovary0 00 of 4 0.00Down
Testis42 04 of 4 2.40Up
Male accessory glands6 10 of 4 0.30Down
Virgin spermatheca1 00 of 4 0.10Down
Mated spermatheca0 00 of 4 0.04Down
Adult carcass1 00 of 4 0.10Down
Larval CNS16 103 of 4 0.93None
Larval Salivary gland5 10 of 4 0.32Down
Larval midgut5 10 of 4 0.30Down
Larval tubule1 00 of 4 0.10Down
Larval hindgut2 10 of 4 0.13Down
Larval fat body11 51 of 4 0.60None
Larval trachea558 3534 of 431.11None
Larval carcass64 314 of 4 3.57None
S2 cells (growing)0 00 of 4 0.02Down
Whole fly18 24 of 4

Looking for FBgn0024294. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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