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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0024740 through 18771 annotations produced 1 hits

Lipase 2 (Lip2):

Annotation Number : CG17116
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0024740
Gbrowse : chr2L:10702394-10706190 (-) // 100.0 //
Probeset : 1633667_at
Accessions : protein= NP_524667;, nucleotide= NM_079928;
Interpro : 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0004806 // triglyceride l
FlyMine data for FBgn0024740.
Homophila reports that CG17116 is a close match (2e-22) to human gene LIPA (NP_000226), a gene associated with Cholesteryl ester storage disease (3);Wolman disease (3).
VDRC has 3 RNAi stocks for FBgn0024740 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain3 10 of 4 0.40Down
Head39 54 of 4 4.20Up
Eye15 33 of 4 1.66None
Thoracicoabdominal ganglion3 10 of 4 0.40Down
Salivary gland9 30 of 4 0.95None
Crop5 20 of 4 0.60None
Midgut4 10 of 4 0.40Down
Tubule4 10 of 4 0.50Down
Hindgut4 21 of 4 0.50None
Heart16 24 of 4 1.69None
Fat body40 74 of 4 4.26Up
Ovary3 00 of 4 0.40Down
Testis90 124 of 4 9.60Up
Male accessory glands6 10 of 4 0.70None
Virgin spermatheca31 34 of 4 3.30Up
Mated spermatheca19 13 of 4 2.07Up
Adult carcass22 23 of 4 2.40Up
Larval CNS2 20 of 4 0.27Down
Larval Salivary gland5 10 of 4 0.55None
Larval midgut5 20 of 4 0.58None
Larval tubule3 00 of 4 0.40Down
Larval hindgut4 10 of 4 0.42Down
Larval fat body57 64 of 4 6.00Up
Larval trachea5 12 of 4 0.61Down
Larval carcass12 22 of 4 1.27None
S2 cells (growing)2 10 of 4 0.24Down
Whole fly9 12 of 4

Looking for FBgn0024740. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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