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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0024841 through 18771 annotations produced 1 hits

pterin-4a-carbinolamine dehydratase (Pcd):

Annotation Number : CG1963
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0024841
Gbrowse : chr3R:25548882-25549948 (+) // 100.0 //
Probeset : 1630167_at
Accessions : protein= NP_477360;, nucleotide= NM_058012;
Interpro : 0005515 // protein binding // inferred from physical interaction /// 0008124 // 4-alpha-hydroxytetrahydrobiopterin dehyd
FlyMine data for FBgn0024841.
BDGP gene expression has embryonic in situ data for Pcd: 6 pix of staining in 1 body parts.
Homophila reports that CG1963 is a close match (6e-29) to human gene DCOH;PCBD (NP_000272), a gene associated with Hyperphenylalaninemia due to pterin-4a-carbinolamine dehydratase deficiency, 264070 (3).
BioGrid reports that CG1963 interacts with CG9424 .
VDRC has 4 RNAi stocks for FBgn0024841 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain392 104 of 4 1.20Up
Head510 194 of 4 1.50Up
Eye686 214 of 4 2.02Up
Thoracicoabdominal ganglion322 84 of 4 1.00None
Salivary gland97 74 of 4 0.29Down
Crop584 54 of 4 1.70Up
Midgut122 84 of 4 0.40Down
Tubule85 24 of 4 0.30Down
Hindgut239 114 of 4 0.70Down
Heart329 224 of 4 0.97None
Fat body410 584 of 4 1.21None
Ovary522 94 of 4 1.50Up
Testis121 74 of 4 0.40Down
Male accessory glands59 54 of 4 0.20Down
Virgin spermatheca1177 904 of 4 3.47Up
Mated spermatheca1082 914 of 4 3.19Up
Adult carcass351 154 of 4 1.00None
Larval CNS291 74 of 4 0.86Down
Larval Salivary gland74 34 of 4 0.22Down
Larval midgut80 54 of 4 0.24Down
Larval tubule145 104 of 4 0.40Down
Larval hindgut265 124 of 4 0.78Down
Larval fat body1034 854 of 4 3.00Up
Larval trachea815 264 of 4 2.40Up
Larval carcass991 784 of 4 2.92Up
S2 cells (growing)873 34 of 4 2.57Up
Whole fly339 154 of 4

Looking for FBgn0024841. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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