FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0025334 through 18771 annotations produced 1 hits

Putative homeodomain protein (PHDP):

Annotation Number : CG11182
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0025334
Gbrowse : chr2R:19770707-19771835 (-) // 100.0 //
Probeset : 1639247_at
Accessions : protein= NP_523834;, nucleotide= NM_079110;
Pathway : DNA-dependent // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from sequen
Interpro : 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic
FlyMine data for FBgn0025334.
Homophila reports that CG11182 is a close match (4e-11) to human gene KTCN;PPCD;PPD;RINX;VSX1 (NP_955457), a gene associated with Corneal dystrophy, hereditary polymorphous posterior, 122000 (3);Craniofacial anomalies, empty sella turcica, corneal endothelial changes, and abnormal retinal and auditory bipolar cells (3);Keratoconus, 148300 (3).
BioGrid reports that CG11182 interacts with CG14168 CG1422 CG1676 CG7492 CG8228 CG11248 CG12812 CG13742 CG1467 CG15505 CG17342 CG3035 CG32772 CG33156 CG5111 CG5701 CG7417 CG8831 CG9331 CG1133 .
VDRC has 1 RNAi stocks for FBgn0025334 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	19 ± 1	4 of 4	5.10	Up
Head	10 ± 1	2 of 4	2.60	Up
Eye	5 ± 0	0 of 4	1.42	None
Thoracicoabdominal ganglion	23 ± 1	4 of 4	6.20	Up
Salivary gland	5 ± 2	0 of 4	1.52	None
Crop	4 ± 0	0 of 4	1.30	None
Midgut	8 ± 0	0 of 4	2.20	Up
Tubule	3 ± 0	0 of 4	1.00	None
Hindgut	5 ± 2	0 of 4	1.30	None
Heart	3 ± 1	0 of 4	0.86	None
Fat body	9 ± 4	2 of 4	2.58	None
Ovary	1 ± 0	0 of 4	0.30	None
Testis	5 ± 1	2 of 4	1.30	None
Male accessory glands	17 ± 1	3 of 4	4.60	Up
Virgin spermatheca	4 ± 1	0 of 4	1.17	None
Mated spermatheca	6 ± 0	0 of 4	1.72	None
Adult carcass	9 ± 3	1 of 4	2.50	None
Larval CNS	24 ± 1	4 of 4	6.56	Up
Larval Salivary gland	4 ± 1	0 of 4	1.26	None
Larval midgut	5 ± 1	0 of 4	1.36	None
Larval tubule	4 ± 0	0 of 4	1.10	None
Larval hindgut	3 ± 1	0 of 4	0.83	None
Larval fat body	8 ± 1	1 of 4	2.20	None
Larval trachea	2 ± 2	0 of 4	0.74	None
Larval carcass	8 ± 1	1 of 4	2.15	None
S2 cells (growing)	2 ± 0	0 of 4	0.68	None
Whole fly	3 ± 1	0 of 4

Looking for FBgn0025334. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720