FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0025454 through 18771 annotations produced 1 hits

CYP6-like (Cyp6g1):

Annotation Number : CG8453
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0025454
Gbrowse : chr2R:8073167-8075934 (+) // 100.0 //
Probeset : 1625697_at
Accessions : protein= NP_610743;, nucleotide= NM_136899;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0025454.
Homophila reports that CG8453 is a close match (8e-11) to human gene CYP11B1;FHI;P450C11 (NP_000488), a gene associated with Adrenal hyperplasia, congenital, due to 11-beta-hydroxylase deficiency, 202010 (3);Aldosteronism, glucocorticoid-remediable, 103900 (3).
VDRC has 3 RNAi stocks for FBgn0025454 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	21 ± 2	4 of 4	0.00	Down
Head	1469 ± 142	4 of 4	3.40	Up
Eye	568 ± 38	4 of 4	1.30	None
Thoracicoabdominal ganglion	21 ± 8	2 of 4	0.00	Down
Salivary gland	8 ± 4	0 of 4	0.02	Down
Crop	21 ± 2	4 of 4	0.00	Down
Midgut	1852 ± 33	4 of 4	4.20	Up
Tubule	5542 ± 1174	4 of 4	12.70	Up
Hindgut	145 ± 17	4 of 4	0.30	Down
Heart	929 ± 103	4 of 4	2.13	Up
Fat body	2456 ± 52	4 of 4	5.62	Up
Ovary	1 ± 0	0 of 4	0.00	Down
Testis	2 ± 1	1 of 4	0.00	Down
Male accessory glands	27 ± 3	2 of 4	0.10	Down
Virgin spermatheca	4664 ± 111	4 of 4	10.67	Up
Mated spermatheca	2505 ± 286	4 of 4	5.73	Up
Adult carcass	1297 ± 147	4 of 4	3.00	Up
Larval CNS	3 ± 1	0 of 4	0.01	Down
Larval Salivary gland	37 ± 3	4 of 4	0.09	Down
Larval midgut	340 ± 108	4 of 4	0.78	None
Larval tubule	88 ± 19	4 of 4	0.20	Down
Larval hindgut	30 ± 5	4 of 4	0.07	Down
Larval fat body	4886 ± 667	4 of 4	11.20	Up
Larval trachea	16 ± 7	3 of 4	0.04	Down
Larval carcass	17 ± 7	3 of 4	0.04	Down
S2 cells (growing)	2 ± 0	0 of 4	0.01	Down
Whole fly	437 ± 53	4 of 4

Looking for FBgn0025454. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720