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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0025725 through 18771 annotations produced 1 hits

alpha-coatomer protein (alphaCop):

Annotation Number : CG7961
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0025725
Gbrowse : chr3L:1641057-1645213 (-) // 100.0 //
Probeset : 1632109_s_at
Accessions : protein= NP_477395; /// NP_728648;, nucleotide= NM_058047; /// NM_167908;
Pathway : Golgi to ER // inferred from sequence or structural similarity /// 0006890 // retrograde vesicle-mediated transport
Interpro : Golgi to ER // non-traceable author statement /// 0006911 // phagocytosis
FlyMine data for FBgn0025725.
BDGP gene expression has embryonic in situ data for alphaCop: 17 pix of staining in 26 body parts.
Homophila reports that CG7961 is a close match (2e-11) to human gene GNB3 (NP_002066), a gene associated with {Hypertension, essential, susceptibility to}, 145500 (3).
BioGrid reports that CG7961 interacts with CG9543 CG8942 .
TRiP has 2 RNAi stocks for FBgn0025725 available for purchase.
VDRC has 2 RNAi stocks for FBgn0025725 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain363 94 of 4 1.10Up
Head380 114 of 4 1.10Up
Eye362 34 of 4 1.09Up
Thoracicoabdominal ganglion403 114 of 4 1.20Up
Salivary gland2169 904 of 4 6.53Up
Crop466 84 of 4 1.40Up
Midgut503 184 of 4 1.50Up
Tubule448 324 of 4 1.30Up
Hindgut470 34 of 4 1.40Up
Heart435 144 of 4 1.31Up
Fat body563 184 of 4 1.70Up
Ovary436 104 of 4 1.30Up
Testis137 54 of 4 0.40Down
Male accessory glands1824 444 of 4 5.50Up
Virgin spermatheca913 1364 of 4 2.75Up
Mated spermatheca1185 1354 of 4 3.57Up
Adult carcass388 144 of 4 1.20Up
Larval CNS491 94 of 4 1.48Up
Larval Salivary gland3300 854 of 4 9.94Up
Larval midgut558 254 of 4 1.68Up
Larval tubule532 154 of 4 1.60Up
Larval hindgut676 244 of 4 2.04Up
Larval fat body471 284 of 4 1.40Up
Larval trachea737 1224 of 4 2.22Up
Larval carcass606 314 of 4 1.83Up
S2 cells (growing)1051 154 of 4 3.17Up
Whole fly332 34 of 4

Looking for FBgn0025725. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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