FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0025879 through 18771 annotations produced 2 hits

tissue inhibitor of metalloproteases (Timp):

Annotation Number : CG6281
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0025879
Gbrowse : chr3R:6029615-6038710 (-) // 100.0 //
Probeset : 1641476_a_at
Accessions : protein= NP_524301; /// NP_731461;, nucleotide= NM_079577; /// NM_169336;
Pathway : open tracheal system // inferred from mutant phenotype /// 0007472 // wing disc morphogenesis // inferred from mutant p
Interpro : 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region /
FlyMine data for FBgn0025879.
BDGP gene expression has embryonic in situ data for Timp: 37 pix of staining in 4 body parts.
Homophila reports that CG6281 is a close match (3e-11) to human gene SFD;TIMP3 (NP_000353), a gene associated with Sorsby fundus dystrophy, 136900 (3).
BioGrid reports that CG6281 interacts with CG4859 CG1794 .
VDRC has 3 RNAi stocks for FBgn0025879 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	358 ± 16	4 of 4	1.60	Up
Head	482 ± 4	4 of 4	2.10	Up
Eye	596 ± 44	4 of 4	2.61	Up
Thoracicoabdominal ganglion	620 ± 12	4 of 4	2.70	Up
Salivary gland	1589 ± 15	4 of 4	6.96	Up
Crop	1257 ± 14	4 of 4	5.50	Up
Midgut	117 ± 7	4 of 4	0.50	Down
Tubule	111 ± 10	4 of 4	0.50	Down
Hindgut	557 ± 7	4 of 4	2.40	Up
Heart	1038 ± 14	4 of 4	4.55	Up
Fat body	839 ± 82	4 of 4	3.68	Up
Ovary	65 ± 2	4 of 4	0.30	Down
Testis	124 ± 8	4 of 4	0.50	Down
Male accessory glands	600 ± 25	4 of 4	2.60	Up
Virgin spermatheca	300 ± 12	4 of 4	1.32	Up
Mated spermatheca	294 ± 6	4 of 4	1.29	Up
Adult carcass	598 ± 20	4 of 4	2.60	Up
Larval CNS	28 ± 1	4 of 4	0.13	Down
Larval Salivary gland	14 ± 1	2 of 4	0.06	Down
Larval midgut	63 ± 5	4 of 4	0.28	Down
Larval tubule	18 ± 2	4 of 4	0.10	Down
Larval hindgut	246 ± 12	4 of 4	1.08	None
Larval fat body	47 ± 3	4 of 4	0.20	Down
Larval trachea	77 ± 27	4 of 4	0.34	Down
Larval carcass	539 ± 28	4 of 4	2.36	Up
S2 cells (growing)	27 ± 2	4 of 4	0.12	Down
Whole fly	228 ± 13	4 of 4

tissue inhibitor of metalloproteases (Timp):

Annotation Number : CG6281
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0025879
Gbrowse : chr3R:6029589-6038710 (-) // 100.0 //
Probeset : 1632533_at
Accessions : protein= NP_524301; /// NP_731461;, nucleotide= NM_079577; /// NM_169336;
Pathway : open tracheal system // inferred from mutant phenotype /// 0007472 // wing disc morphogenesis // inferred from mutant p
Interpro : 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region /
FlyMine data for FBgn0025879.
BDGP gene expression has embryonic in situ data for Timp: 37 pix of staining in 4 body parts.
Homophila reports that CG6281 is a close match (3e-11) to human gene SFD;TIMP3 (NP_000353), a gene associated with Sorsby fundus dystrophy, 136900 (3).
BioGrid reports that CG6281 interacts with CG4859 CG1794 .
VDRC has 3 RNAi stocks for FBgn0025879 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	381 ± 38	4 of 4	1.60	Up
Head	517 ± 29	4 of 4	2.10	Up
Eye	693 ± 29	4 of 4	2.86	Up
Thoracicoabdominal ganglion	765 ± 22	4 of 4	3.20	Up
Salivary gland	746 ± 19	4 of 4	3.07	Up
Crop	1253 ± 9	4 of 4	5.20	Up
Midgut	90 ± 3	4 of 4	0.40	Down
Tubule	240 ± 26	4 of 4	1.00	None
Hindgut	523 ± 6	4 of 4	2.20	Up
Heart	1333 ± 39	4 of 4	5.49	Up
Fat body	771 ± 76	4 of 4	3.18	Up
Ovary	57 ± 3	4 of 4	0.20	Down
Testis	100 ± 7	4 of 4	0.40	Down
Male accessory glands	505 ± 16	4 of 4	2.10	Up
Virgin spermatheca	1037 ± 20	4 of 4	4.27	Up
Mated spermatheca	1140 ± 33	4 of 4	4.70	Up
Adult carcass	614 ± 39	4 of 4	2.50	Up
Larval CNS	35 ± 3	4 of 4	0.15	Down
Larval Salivary gland	12 ± 1	2 of 4	0.05	Down
Larval midgut	56 ± 7	4 of 4	0.23	Down
Larval tubule	24 ± 2	4 of 4	0.10	Down
Larval hindgut	255 ± 8	4 of 4	1.05	None
Larval fat body	53 ± 5	4 of 4	0.20	Down
Larval trachea	79 ± 16	4 of 4	0.33	Down
Larval carcass	458 ± 17	4 of 4	1.89	Up
S2 cells (growing)	19 ± 4	3 of 4	0.08	Down
Whole fly	242 ± 26	4 of 4

Looking for FBgn0025879. 2 entries matched from 18771, in 0 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720