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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0026375 through 18771 annotations produced 1 hits

Rp190RhoGAP (RhoGAPp190):

Annotation Number : CG32555
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0026375
Gbrowse : chrX:17533179-17546585 (-) // 99.94 //
Probeset : 1638199_s_at
Accessions : protein= NP_573231; /// NP_728089; /// NP_728090;, nucleotide= NM_133003; /// NM_167572; /// NM_167573;
Pathway : 0005622 // intracellular // inferred from electronic annotation
Interpro : 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity
FlyMine data for FBgn0026375.
BDGP gene expression has embryonic in situ data for RhoGAPp190: 4 pix of staining in 1 body parts.
Homophila reports that CG32555 is a close match (6e-11) to human gene CHN1;CHN;ARHGAP2;RHOGAP2;DURS2 (NP_001813), a gene associated with Duane retraction syndrome 2, 604356 (3).
BioGrid reports that CG32555 interacts with CG7524 CG3595 CG3595 CG1560 CG8416 .
TRiP has 2 RNAi stocks for FBgn0026375 available for purchase.
VDRC has 3 RNAi stocks for FBgn0026375 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain665 224 of 415.70Up
Head132 84 of 4 3.10Up
Eye119 114 of 4 2.82Up
Thoracicoabdominal ganglion523 224 of 412.40Up
Salivary gland82 14 of 4 1.94Up
Crop92 54 of 4 2.20Up
Midgut62 34 of 4 1.50Up
Tubule42 34 of 4 1.00None
Hindgut79 14 of 4 1.90Up
Heart51 24 of 4 1.21None
Fat body71 94 of 4 1.70Up
Ovary20 24 of 4 0.50Down
Testis27 24 of 4 0.70Down
Male accessory glands40 44 of 4 1.00None
Virgin spermatheca90 34 of 4 2.14Up
Mated spermatheca81 54 of 4 1.92Up
Adult carcass59 32 of 4 1.40Up
Larval CNS612 864 of 414.46Up
Larval Salivary gland55 34 of 4 1.32Up
Larval midgut43 41 of 4 1.04None
Larval tubule50 34 of 4 1.20None
Larval hindgut54 14 of 4 1.29Up
Larval fat body42 14 of 4 1.00None
Larval trachea50 64 of 4 1.18None
Larval carcass50 34 of 4 1.20None
S2 cells (growing)73 24 of 4 1.74Up
Whole fly42 34 of 4

Looking for FBgn0026375. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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