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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0027356 through 18771 annotations produced 1 hits

amphiphysin (Amph):

Annotation Number : CG8604
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0027356
Gbrowse : chr2R:8481087-8499578 (+) // 100.0 //
Probeset : 1627410_at
Accessions : protein= NP_523717;, nucleotide= NM_078993;
Pathway : 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay
Interpro : 0005515 // protein binding // inferred from electronic annotation
FlyMine data for FBgn0027356.
BDGP gene expression has embryonic in situ data for Amph: 38 pix of staining in 13 body parts.
Homophila reports that CG8604 is a close match (1e-40) to human gene AMPHL;BIN1 (NP_647598), a gene associated with Myopathy, centronuclear, autosomal recessive, 255200 (3).
BioGrid reports that CG8604 interacts with CG8831 CG9282 CG1822 .
TRiP has 2 RNAi stocks for FBgn0027356 available for purchase.
VDRC has 2 RNAi stocks for FBgn0027356 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1193 84 of 4 3.00Up
Head673 214 of 4 1.70Up
Eye457 204 of 4 1.16None
Thoracicoabdominal ganglion1323 204 of 4 3.40Up
Salivary gland706 534 of 4 1.79Up
Crop1167 264 of 4 3.00Up
Midgut209 154 of 4 0.50Down
Tubule956 764 of 4 2.40Up
Hindgut1626 404 of 4 4.10Up
Heart751 484 of 4 1.91Up
Fat body326 254 of 4 0.83None
Ovary227 94 of 4 0.60Down
Testis68 54 of 4 0.20Down
Male accessory glands315 74 of 4 0.80Down
Virgin spermatheca185 164 of 4 0.47Down
Mated spermatheca229 204 of 4 0.58Down
Adult carcass703 84 of 4 1.80Up
Larval CNS269 364 of 4 0.68Down
Larval Salivary gland105 54 of 4 0.27Down
Larval midgut444 674 of 4 1.13None
Larval tubule329 164 of 4 0.80None
Larval hindgut1847 1684 of 4 4.69Up
Larval fat body141 114 of 4 0.40Down
Larval trachea266 784 of 4 0.68Down
Larval carcass1139 1424 of 4 2.89Up
S2 cells (growing)27 14 of 4 0.07Down
Whole fly394 234 of 4

Looking for FBgn0027356. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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