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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0027584 through 18771 annotations produced 1 hits



(CG4757):

Annotation Number : CG4757
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0027584
Gbrowse : chr3R:6986923-6988868 (+) // 100.0 //
Probeset : 1638021_at
Accessions : protein= NP_650043;, nucleotide= NM_141786;
Interpro : 0004091 // carboxylesterase activity // inferred from sequence or structural similarity /// 0004091 // carboxylesterase
FlyMine data for FBgn0027584.
BDGP gene expression has embryonic in situ data for BcDNA:GH05741: 4 pix of staining in 1 body parts.
Homophila reports that CG4757 is a close match (3e-25) to human gene AITD3;TG (NP_003226), a gene associated with Goiter, adolescent multinodular (1);Goiter, nonendemic, simple (3);Hypothyroidism, hereditary congenital (3);{Autoimmune thyroid disease, susceptibility to 3}, 608175 (3).
VDRC has 2 RNAi stocks for FBgn0027584 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain8 ± 22 of 4 0.10Down
Head750 ± 544 of 4 8.40Up
Eye652 ± 1034 of 4 7.28Up
Thoracicoabdominal ganglion5 ± 20 of 4 0.10Down
Salivary gland5 ± 20 of 4 0.06Down
Crop15 ± 24 of 4 0.20Down
Midgut1 ± 00 of 4 0.00Down
Tubule33 ± 92 of 4 0.40Down
Hindgut24 ± 83 of 4 0.30Down
Heart12 ± 14 of 4 0.14Down
Fat body175 ± 2914 of 4 1.96None
Ovary14 ± 24 of 4 0.20Down
Testis20 ± 54 of 4 0.20Down
Male accessory glands3 ± 10 of 4 0.00Down
Virgin spermatheca242 ± 864 of 4 2.71None
Mated spermatheca379 ± 1364 of 4 4.24None
Adult carcass296 ± 764 of 4 3.30None
Larval CNS1 ± 10 of 4 0.02Down
Larval Salivary gland2 ± 00 of 4 0.03Down
Larval midgut0 ± 00 of 4 0.01Down
Larval tubule211 ± 174 of 4 2.40Up
Larval hindgut3 ± 00 of 4 0.04Down
Larval fat body63 ± 492 of 4 0.70None
Larval trachea203 ± 1724 of 4 2.27None
Larval carcass19 ± 44 of 4 0.22Down
S2 cells (growing)1 ± 00 of 4 0.02Down
Whole fly89 ± 194 of 4

Looking for FBgn0027584. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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