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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0028381 through 18771 annotations produced 1 hits

caspase-3 protein (decay):

Annotation Number : CG14902
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0028381
Gbrowse : chr3R:12324779-12327394 (-) // 100.0 //
Probeset : 1622960_at
Accessions : protein= NP_477462;, nucleotide= NM_058114;
Pathway : 0005737 // cytoplasm // inferred from direct assay
Interpro : 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase
FlyMine data for FBgn0028381.
BDGP gene expression has embryonic in situ data for decay: 15 pix of staining in 2 body parts.
Homophila reports that CG14902 is a close match (2e-27) to human gene ALPS2;CASP10;MCH4 (NP_116756), a gene associated with Autoimmune lymphoproliferative syndrome, type II, 603909 (3);Gastric cancer, somatic, 137215 (3);Non-Hodgkin lymphoma, somatic, 605027 (3).
VDRC has 3 RNAi stocks for FBgn0028381 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain0 00 of 4 0.00Down
Head7 10 of 4 0.00Down
Eye4 11 of 4 0.03Down
Thoracicoabdominal ganglion0 00 of 4 0.00Down
Salivary gland8 50 of 4 0.05Down
Crop9 12 of 4 0.10Down
Midgut2023 734 of 412.10Up
Tubule877 254 of 4 5.30Up
Hindgut453 254 of 4 2.70Up
Heart3 00 of 4 0.02Down
Fat body6 40 of 4 0.04Down
Ovary2 00 of 4 0.00Down
Testis26 04 of 4 0.20Down
Male accessory glands4 10 of 4 0.00Down
Virgin spermatheca3 10 of 4 0.02Down
Mated spermatheca3 00 of 4 0.02Down
Adult carcass9 30 of 4 0.10Down
Larval CNS3 10 of 4 0.02Down
Larval Salivary gland10 23 of 4 0.06Down
Larval midgut2009 624 of 412.03Up
Larval tubule750 234 of 4 4.50Up
Larval hindgut455 344 of 4 2.73Up
Larval fat body445 614 of 4 2.70Up
Larval trachea4 20 of 4 0.03Down
Larval carcass4 10 of 4 0.03Down
S2 cells (growing)1 10 of 4 0.01Down
Whole fly167 134 of 4

Looking for FBgn0028381. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

measure downtime