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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0028434 through 18771 annotations produced 1 hits

Ercc1 (Ercc1):

Annotation Number : CG10215
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0028434
Gbrowse : chr2R:10740469-10741453 (+) // 100.0 //
Probeset : 1640079_at
Accessions : protein= NP_477468;, nucleotide= NM_058120;
Pathway : DNA incision
Interpro : 5'-to lesion // inferred from sequence or structural similarity /// 0007131 // reciprocal meiotic recombination // infe
FlyMine data for FBgn0028434.
Homophila reports that CG10215 is a close match (5e-53) to human gene COFS4;ERCC1;UV20 (NP_973730), a gene associated with Cerebrooculofacioskeletal syndrome 4, 610758 (3).
BioGrid reports that CG10215 interacts with CG33052 CG3697 CG6358 CG11164 CG15631 CG17158 CG3052 CG5354 CG5363 CG8642 .
TRiP has 1 RNAi stocks for FBgn0028434 available for purchase.
VDRC has 3 RNAi stocks for FBgn0028434 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain33 24 of 4 0.70Down
Head23 14 of 4 0.50Down
Eye14 14 of 4 0.29Down
Thoracicoabdominal ganglion40 24 of 4 0.80None
Salivary gland25 40 of 4 0.50Down
Crop35 44 of 4 0.70None
Midgut20 21 of 4 0.40Down
Tubule23 13 of 4 0.50Down
Hindgut26 23 of 4 0.50Down
Heart21 04 of 4 0.42Down
Fat body23 73 of 4 0.48Down
Ovary84 34 of 4 1.70Up
Testis25 34 of 4 0.50Down
Male accessory glands36 21 of 4 0.70Down
Virgin spermatheca15 10 of 4 0.31Down
Mated spermatheca17 31 of 4 0.35Down
Adult carcass18 50 of 4 0.40Down
Larval CNS57 44 of 4 1.15None
Larval Salivary gland40 33 of 4 0.82None
Larval midgut9 30 of 4 0.19Down
Larval tubule26 14 of 4 0.50Down
Larval hindgut26 34 of 4 0.53Down
Larval fat body23 42 of 4 0.50Down
Larval trachea50 44 of 4 1.00None
Larval carcass31 12 of 4 0.63Down
S2 cells (growing)46 34 of 4 0.93None
Whole fly49 44 of 4

Looking for FBgn0028434. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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