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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0029093 through 18771 annotations produced 1 hits

cathepsin D (cathD):

Annotation Number : CG1548
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0029093
Gbrowse : chr2R:3709614-3711073 (-) // 100.0 //
Probeset : 1631493_at
Accessions : protein= NP_652013;, nucleotide= NM_143756;
Pathway : 0005875 // microtubule associated complex // inferred from direct assay
Interpro : 0004190 // aspartic-type endopeptidase activity // inferred from sequence or structural similarity /// 0004190 // aspart
FlyMine data for FBgn0029093.
BDGP gene expression has embryonic in situ data for cathD: 42 pix of staining in 21 body parts.
Homophila reports that CG1548 is a close match (5e-85) to human gene REN (NP_000528), a gene associated with Renal tubular dysgenesis, 267430 (3);[Hyperproreninemia] (3).
BioGrid reports that CG1548 interacts with CG3075 CG5352 .
TRiP has 1 RNAi stocks for FBgn0029093 available for purchase.
VDRC has 2 RNAi stocks for FBgn0029093 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1570 404 of 4 1.10None
Head2465 704 of 4 1.70Up
Eye2985 1364 of 4 2.00Up
Thoracicoabdominal ganglion1998 384 of 4 1.30Up
Salivary gland1645 2084 of 4 1.10None
Crop2303 304 of 4 1.50Up
Midgut2534 444 of 4 1.70Up
Tubule2644 534 of 4 1.80Up
Hindgut2251 384 of 4 1.50Up
Heart4611 2304 of 4 3.09Up
Fat body3947 3274 of 4 2.65Up
Ovary1049 184 of 4 0.70Down
Testis589 44 of 4 0.40Down
Male accessory glands1072 404 of 4 0.70Down
Virgin spermatheca2045 604 of 4 1.37Up
Mated spermatheca1451 564 of 4 0.97None
Adult carcass3424 384 of 4 2.30Up
Larval CNS1359 304 of 4 0.91Down
Larval Salivary gland783 184 of 4 0.53Down
Larval midgut5198 1984 of 4 3.49Up
Larval tubule4311 514 of 4 2.90Up
Larval hindgut3091 1324 of 4 2.07Up
Larval fat body7818 9154 of 4 5.20Up
Larval trachea1770 634 of 4 1.19Up
Larval carcass2390 1754 of 4 1.60Up
S2 cells (growing)2943 574 of 4 1.97Up
Whole fly1490 274 of 4

Looking for FBgn0029093. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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