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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0029174 through 18771 annotations produced 1 hits

FK506-binding protein FKBP59 (FKBP59):

Annotation Number : CG4535
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0029174
Gbrowse : chr2L:9888033-9890120 (+) // 100.0 //
Probeset : 1624150_at
Accessions : protein= NP_524895;, nucleotide= NM_080156;
Pathway : 0016027 // inaD signaling complex // inferred from physical interaction
Interpro : 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from sequence or structural similarity /// 0003755 /
FlyMine data for FBgn0029174.
BDGP gene expression has embryonic in situ data for FKBP59: 20 pix of staining in 11 body parts.
Homophila reports that CG4535 is a close match (1e-82) to human gene FKBP5;FKBP51 (NP_004108), a gene associated with {Major depressive disorder and accelerated response to antidepressant drug treatment}, 608516 (3).
TRiP has 2 RNAi stocks for FBgn0029174 available for purchase.
VDRC has 2 RNAi stocks for FBgn0029174 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain429 124 of 4 0.70Down
Head333 134 of 4 0.60Down
Eye398 244 of 4 0.67Down
Thoracicoabdominal ganglion458 204 of 4 0.80Down
Salivary gland146 144 of 4 0.25Down
Crop284 114 of 4 0.50Down
Midgut166 84 of 4 0.30Down
Tubule259 204 of 4 0.40Down
Hindgut236 34 of 4 0.40Down
Heart883 704 of 4 1.48Up
Fat body766 284 of 4 1.28Up
Ovary832 144 of 4 1.40Up
Testis371 154 of 4 0.60Down
Male accessory glands444 294 of 4 0.70Down
Virgin spermatheca263 104 of 4 0.44Down
Mated spermatheca315 44 of 4 0.53Down
Adult carcass447 294 of 4 0.70Down
Larval CNS707 554 of 4 1.18Up
Larval Salivary gland476 34 of 4 0.80Down
Larval midgut156 64 of 4 0.26Down
Larval tubule190 144 of 4 0.30Down
Larval hindgut303 44 of 4 0.51Down
Larval fat body251 154 of 4 0.40Down
Larval trachea579 554 of 4 0.97None
Larval carcass376 474 of 4 0.63Down
S2 cells (growing)734 64 of 4 1.23Up
Whole fly597 144 of 4

Looking for FBgn0029174. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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