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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0029843 through 18771 annotations produced 1 hits

Neprilysin 1 (Nep1):

Annotation Number : CG5905
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0029843
Gbrowse : chrX:5985802-5998006 (+) // 100.0 //
Probeset : 1639483_s_at
Accessions : protein= NP_511056; /// NP_727065;, nucleotide= NM_078501; /// NM_167059;
Interpro : 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendope
FlyMine data for FBgn0029843.
BDGP gene expression has embryonic in situ data for Nep1: 21 pix of staining in 5 body parts.
Homophila reports that CG5905 is a close match (7e-81) to human gene KEL (NP_000411), a gene associated with [Blood group, Kell] (3).
BioGrid reports that CG5905 interacts with CG9925 .
VDRC has 5 RNAi stocks for FBgn0029843 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain169 54 of 4 5.80Up
Head105 54 of 4 3.60Up
Eye146 224 of 4 5.01Up
Thoracicoabdominal ganglion53 24 of 4 1.80Up
Salivary gland7 30 of 4 0.27Down
Crop2 00 of 4 0.10Down
Midgut99 94 of 4 3.40Up
Tubule4 30 of 4 0.20Down
Hindgut52 24 of 4 1.80Up
Heart7 20 of 4 0.24Down
Fat body10 31 of 4 0.34Down
Ovary8 00 of 4 0.30Down
Testis41 24 of 4 1.40Up
Male accessory glands2 00 of 4 0.10Down
Virgin spermatheca47 24 of 4 1.62Up
Mated spermatheca45 24 of 4 1.56Up
Adult carcass42 44 of 4 1.50None
Larval CNS67 94 of 4 2.32Up
Larval Salivary gland14 10 of 4 0.48Down
Larval midgut77 84 of 4 2.65Up
Larval tubule1 00 of 4 0.00Down
Larval hindgut15 10 of 4 0.52Down
Larval fat body1 00 of 4 0.10Down
Larval trachea18 24 of 4 0.64Down
Larval carcass169 134 of 4 5.80Up
S2 cells (growing)3 10 of 4 0.11Down
Whole fly29 24 of 4

Looking for FBgn0029843. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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