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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0031081 through 18771 annotations produced 1 hits



Neprilysin 3 (Nep3):

Annotation Number : CG9565
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0031081
Gbrowse : chrX:19855721-19862516 (+) // 99.66 //
Probeset : 1632972_at
Accessions : protein= NP_523417;, nucleotide= NM_078693;
Interpro : 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendope
FlyMine data for FBgn0031081.
Homophila reports that CG9565 is a close match (1e-79) to human gene KEL (NP_000411), a gene associated with [Blood group, Kell] (3).
VDRC has 2 RNAi stocks for FBgn0031081 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain387 ± 154 of 416.10Up
Head94 ± 64 of 4 4.00Up
Eye39 ± 74 of 4 1.63None
Thoracicoabdominal ganglion437 ± 94 of 418.20Up
Salivary gland250 ± 194 of 410.44Up
Crop162 ± 64 of 4 6.80Up
Midgut63 ± 54 of 4 2.60Up
Tubule80 ± 54 of 4 3.30Up
Hindgut141 ± 64 of 4 5.90Up
Heart35 ± 34 of 4 1.48Up
Fat body11 ± 34 of 4 0.47Down
Ovary3 ± 11 of 4 0.20Down
Testis5 ± 02 of 4 0.20Down
Male accessory glands30 ± 24 of 4 1.30None
Virgin spermatheca10 ± 21 of 4 0.42Down
Mated spermatheca13 ± 13 of 4 0.55Down
Adult carcass21 ± 53 of 4 0.90None
Larval CNS189 ± 194 of 4 7.91Up
Larval Salivary gland7 ± 20 of 4 0.31Down
Larval midgut61 ± 44 of 4 2.55Up
Larval tubule469 ± 304 of 419.60Up
Larval hindgut117 ± 54 of 4 4.89Up
Larval fat body3 ± 00 of 4 0.20Down
Larval trachea6 ± 12 of 4 0.26Down
Larval carcass65 ± 54 of 4 2.74Up
S2 cells (growing)3 ± 00 of 4 0.14Down
Whole fly24 ± 24 of 4

Looking for FBgn0031081. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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