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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0031461 through 18771 annotations produced 1 hits

dActivin2 (daw):

Annotation Number : CG16987
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0031461
Gbrowse : chr2L:2805517-2812147 (+) // 100.0 //
Probeset : 1626766_s_at
Accessions : protein= NP_523461; /// NP_722840;, nucleotide= NM_078737; /// NM_164503;
Interpro : 0005160 // transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 00055
FlyMine data for FBgn0031461.
BDGP gene expression has embryonic in situ data for Alp23B: 25 pix of staining in 9 body parts.
Homophila reports that CG16987 is a close match (3e-11) to human gene TGFB3 (NP_003230), a gene associated with Arrhythmogenic right ventricular dysplasia 1, 107970 (3).
BioGrid reports that CG16987 interacts with CG7538 CG3838 CG18412 .
TRiP has 1 RNAi stocks for FBgn0031461 available for purchase.
VDRC has 2 RNAi stocks for FBgn0031461 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain40 44 of 4 0.30Down
Head296 134 of 4 2.30Up
Eye135 174 of 4 1.04None
Thoracicoabdominal ganglion43 24 of 4 0.30Down
Salivary gland6 20 of 4 0.05Down
Crop13 12 of 4 0.10Down
Midgut110 134 of 4 0.90None
Tubule14 31 of 4 0.10Down
Hindgut93 64 of 4 0.70None
Heart331 64 of 4 2.55Up
Fat body715 504 of 4 5.50Up
Ovary31 54 of 4 0.20Down
Testis5 11 of 4 0.00Down
Male accessory glands9 21 of 4 0.10Down
Virgin spermatheca187 134 of 4 1.44Up
Mated spermatheca510 244 of 4 3.92Up
Adult carcass325 194 of 4 2.50Up
Larval CNS100 204 of 4 0.78None
Larval Salivary gland30 64 of 4 0.24Down
Larval midgut213 264 of 4 1.64Up
Larval tubule12 10 of 4 0.10Down
Larval hindgut288 234 of 4 2.22Up
Larval fat body1500 684 of 411.50Up
Larval trachea90 184 of 4 0.70None
Larval carcass231 174 of 4 1.78Up
S2 cells (growing)86 44 of 4 0.67None
Whole fly130 174 of 4

Looking for FBgn0031461. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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