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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0031804 through 18771 annotations produced 1 hits

Fibrinogen-related protein (CG9500):

Annotation Number : CG9500
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0031804
Gbrowse : chr2L:6357250-6358170 (-) // 100.0 //
Probeset : 1625468_at
Accessions : protein= NP_609018;, nucleotide= NM_135174;
Pathway : 0005576 // extracellular region // inferred from sequence or structural similarity
Interpro : 0005102 // receptor binding // inferred from electronic annotation
FlyMine data for FBgn0031804.
Homophila reports that CG9500 is a close match (4e-22) to human gene FGG (NP_068656), a gene associated with Dysfibrinogenemia, gamma type (3);Hypofibrinogenemia, gamma type (3);Thrombophilia, dysfibrinogenemic (3).

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1 00 of 4 0.80None
Head1 00 of 4 0.80None
Eye2 00 of 4 1.48None
Thoracicoabdominal ganglion3 00 of 4 2.40None
Salivary gland12 20 of 4 9.20Up
Crop2 10 of 4 1.90None
Midgut2 10 of 4 1.80None
Tubule2 00 of 4 1.50Up
Hindgut2 10 of 4 1.70None
Heart1 10 of 4 1.25None
Fat body0 00 of 4 0.45None
Ovary0 00 of 4 0.70None
Testis20 14 of 414.90Up
Male accessory glands6 20 of 4 4.90None
Virgin spermatheca0 00 of 4 0.34Down
Mated spermatheca1 00 of 4 0.91None
Adult carcass1 00 of 4 1.20None
Larval CNS1 00 of 4 1.00None
Larval Salivary gland4 10 of 4 3.13None
Larval midgut2 00 of 4 1.48None
Larval tubule1 00 of 4 1.30None
Larval hindgut0 00 of 4 0.43None
Larval fat body6 30 of 4 4.90None
Larval trachea1 00 of 4 0.71None
Larval carcass0 00 of 4 0.48None
S2 cells (growing)3 00 of 4 2.66None
Whole fly1 00 of 4

Looking for FBgn0031804. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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