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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0033051 through 18771 annotations produced 1 hits

Strica (dream):

Annotation Number : CG7863
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033051
Gbrowse : chr2R:1908371-1910711 (-) // 100.0 //
Probeset : 1632790_at
Accessions : protein= NP_610193;, nucleotide= NM_136349;
Pathway : 0005737 // cytoplasm // inferred from direct assay
Interpro : 0004197 // cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0004197 // cystei
FlyMine data for FBgn0033051.
BDGP gene expression has embryonic in situ data for dream: 4 pix of staining in 1 body parts.
Homophila reports that CG7863 is a close match (5e-11) to human gene ALPS2;CASP10;MCH4 (NP_001221), a gene associated with Autoimmune lymphoproliferative syndrome, type II, 603909 (3);Gastric cancer, somatic, 137215 (3);Non-Hodgkin lymphoma, somatic, 605027 (3).
VDRC has 2 RNAi stocks for FBgn0033051 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain6 00 of 4 0.20Down
Head11 30 of 4 0.30Down
Eye1 00 of 4 0.05Down
Thoracicoabdominal ganglion5 10 of 4 0.10Down
Salivary gland6 40 of 4 0.17Down
Crop3 10 of 4 0.10Down
Midgut212 154 of 4 5.50Up
Tubule183 274 of 4 4.80Up
Hindgut46 14 of 4 1.20Up
Heart18 22 of 4 0.48Down
Fat body15 40 of 4 0.40Down
Ovary79 44 of 4 2.10Up
Testis8 10 of 4 0.20Down
Male accessory glands42 24 of 4 1.10None
Virgin spermatheca24 33 of 4 0.63Down
Mated spermatheca35 43 of 4 0.91None
Adult carcass8 10 of 4 0.20Down
Larval CNS17 31 of 4 0.45Down
Larval Salivary gland251 194 of 4 6.51Up
Larval midgut309 204 of 4 8.03Up
Larval tubule299 94 of 4 7.80Up
Larval hindgut124 44 of 4 3.23Up
Larval fat body170 84 of 4 4.40Up
Larval trachea94 34 of 4 2.44Up
Larval carcass102 64 of 4 2.66Up
S2 cells (growing)721 194 of 418.72Up
Whole fly38 24 of 4

Looking for FBgn0033051. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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